ENSG00000185420


Homo sapiens

Features
Gene ID: ENSG00000185420
  
Biological name :SMYD3
  
Synonyms : Q9H7B4 / SET and MYND domain containing 3 / SMYD3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q44
Gene start: 245749342
Gene end: 246507312
  
Corresponding Affymetrix probe sets: 218788_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419184
Ensembl peptide - ENSP00000375712
Ensembl peptide - ENSP00000487434
Ensembl peptide - ENSP00000385380
Ensembl peptide - ENSP00000408122
Ensembl peptide - ENSP00000394281
NCBI entrez gene - 64754     See in Manteia.
OMIM - 608783
RefSeq - XM_011544258
RefSeq - XM_011544253
RefSeq - XM_011544261
RefSeq - XM_011544260
RefSeq - NM_001167740
RefSeq - NM_022743
RefSeq - XM_017002094
RefSeq - XM_011544259
RefSeq Peptide - NP_073580
RefSeq Peptide - NP_001161212
swissprot - Q9H7B4
swissprot - B0QZA0
swissprot - A8MXR1
swissprot - B0QZ88
swissprot - B0QZ99
Ensembl - ENSG00000185420
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smyd3ENSDARG00000058050Danio rerio
 SMYD3ENSGALG00000010653Gallus gallus
 Smyd3ENSMUSG00000055067Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SMYD1 / Q8NB12 / SET and MYND domain containing 1ENSG0000011559331
SMYD2 / Q9NRG4 / SET and MYND domain containing 2ENSG0000014349931


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR002893  Zinc finger, MYND-type
 IPR025805  Histone-lysine N-methyltransferase Smyd3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006334 nucleosome assembly IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0014904 myotube cell development IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0034968 histone lysine methylation IEA
 biological_processGO:0045184 establishment of protein localization IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0071549 cellular response to dexamethasone stimulus IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000993 RNA polymerase II core binding IEA
 molecular_functionGO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity TAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
PKMTs methylate histone lysines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr