ENSG00000186684


Homo sapiens

Features
Gene ID: ENSG00000186684
  
Biological name :CYP27C1
  
Synonyms : CYP27C1 / cytochrome P450 family 27 subfamily C member 1 / Q4G0S4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q14.3
Gene start: 127184120
Gene end: 127220078
  
Corresponding Affymetrix probe sets: 1568868_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000387198
Ensembl peptide - ENSP00000334128
NCBI entrez gene - 339761     See in Manteia.
RefSeq - XM_017003961
RefSeq - NM_001001665
RefSeq - XM_017003960
RefSeq Peptide - NP_001001665
swissprot - Q4G0S4
swissprot - A0A024RAI7
Ensembl - ENSG00000186684
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A8WGA0ENSDARG00000092660Danio rerio
 ENSGALG00000011532Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O15528 / CYP27B1 / cytochrome P450 family 27 subfamily B member 1ENSG0000011101242
Q02318 / CYP27A1 / cytochrome P450 family 27 subfamily A member 1ENSG0000013592938
Q07973 / CYP24A1 / cytochrome P450 family 24 subfamily A member 1ENSG0000001918632
P19099 / CYP11B2 / cytochrome P450 family 11 subfamily B member 2ENSG0000017914229
P15538 / CYP11B1 / cytochrome P450 family 11 subfamily B member 1ENSG0000016088228
CYP3A5 / P20815 / cytochrome P450 family 3 subfamily A member 5ENSG0000010625828
P24462 / CYP3A7-CYP3A51P / CYP3A7-CYP3A51P readthroughENSG0000028230126
CYP3A4 / P08684 / cytochrome P450 family 3 subfamily A member 4ENSG0000016086826
P05108 / CYP11A1 / cytochrome P450 family 11 subfamily A member 1ENSG0000014045926
CYP3A7 / P24462 / cytochrome P450 family 3 subfamily A member 7ENSG0000016087026
Q9HB55 / CYP3A43 / cytochrome P450 family 3 subfamily A member 43ENSG0000002146125
Q9Y6A2 / CYP46A1 / cytochrome P450 family 46 subfamily A member 1ENSG0000003653021
P24557 / TBXAS1 / thromboxane A synthase 1ENSG0000005937720


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042572 retinol metabolic process IDA
 biological_processGO:0042573 retinoic acid metabolic process IDA
 biological_processGO:0042574 retinal metabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0001972 retinoic acid binding IDA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005502 11-cis retinal binding IDA
 molecular_functionGO:0005503 all-trans retinal binding IDA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061896 all-trans retinol 3,4-desaturase activity IDA
 molecular_functionGO:0061897 all-trans retinal 3,4-desaturase activity IDA
 molecular_functionGO:0061898 all-trans retinoic acid 3,4-desaturase activity IDA
 molecular_functionGO:0061899 11-cis-retinal 3,4-desaturase activity IDA
 molecular_functionGO:1904768 all-trans-retinol binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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