ENSG00000188779


Homo sapiens

Features
Gene ID: ENSG00000188779
  
Biological name :SKOR1
  
Synonyms : P84550 / SKI family transcriptional corepressor 1 / SKOR1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q23
Gene start: 67819704
Gene end: 67834561
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000343200
Ensembl peptide - ENSP00000369374
Ensembl peptide - ENSP00000451193
Ensembl peptide - ENSP00000452361
NCBI entrez gene - 390598     See in Manteia.
OMIM - 611273
RefSeq - XM_017022173
RefSeq - NM_001258024
RefSeq Peptide - NP_001244953
swissprot - G3V3E1
swissprot - P84550
swissprot - G3V5H7
Ensembl - ENSG00000188779
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q1LXZ9ENSDARG00000062448Danio rerio
 skor1aENSDARG00000069030Danio rerio
 SKOR1ENSGALG00000029521Gallus gallus
 Skor1ENSMUSG00000022245Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SKOR2 / Q2VWA4 / SKI family transcriptional corepressor 2ENSG0000021547439
SKI / P12755 / SKI proto-oncogeneENSG0000015793316
SKIL / P12757 / SKI like proto-oncogeneENSG0000013660314


Protein motifs (from Interpro)
Interpro ID Name
 IPR003380  SKI/SNO/DAC domain
 IPR009061  Putative DNA-binding domain superfamily
 IPR010919  SAND-like domain superfamily
 IPR014890  c-SKI SMAD4-binding domain
 IPR023216  Transcription regulator SKI/SnoN
 IPR028762  Ski family transcriptional corepressor 1
 IPR037000  Ski-like, DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IBA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IDA
 biological_processGO:0045596 negative regulation of cell differentiation IBA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0048666 neuron development IBA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0030425 dendrite IDA
 cellular_componentGO:0043025 neuronal cell body IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0046332 SMAD binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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