ENSG00000189058


Homo sapiens

Features
Gene ID: ENSG00000189058
  
Biological name :APOD
  
Synonyms : APOD / apolipoprotein D / P05090
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q29
Gene start: 195568702
Gene end: 195584205
  
Corresponding Affymetrix probe sets: 201525_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391597
Ensembl peptide - ENSP00000415235
Ensembl peptide - ENSP00000393076
Ensembl peptide - ENSP00000345179
NCBI entrez gene - 347     See in Manteia.
OMIM - 107740
RefSeq - NM_001647
RefSeq Peptide - NP_001638
swissprot - C9JX71
swissprot - C9JF17
swissprot - F8WBT9
swissprot - P05090
Ensembl - ENSG00000189058
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 apoda.1ENSDARG00000060345Danio rerio
 apoda.2ENSDARG00000060350Danio rerio
 apodbENSDARG00000057437Danio rerio
 APODENSGALG00000006995Gallus gallus
 ApodENSMUSG00000022548Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000566  Lipocalin/cytosolic fatty-acid binding domain
 IPR002345  Lipocalin
 IPR002969  Apolipoprotein D
 IPR012674  Calycin
 IPR022271  Lipocalin, ApoD type
 IPR022272  Lipocalin family conserved site
 IPR026222  Apolipoprotein D, vertebrates


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000302 response to reactive oxygen species IEA
 biological_processGO:0001525 angiogenesis NAS
 biological_processGO:0006006 glucose metabolic process IDA
 biological_processGO:0006629 lipid metabolic process IDA
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0007420 brain development ISS
 biological_processGO:0007568 aging IEA
 biological_processGO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway IDA
 biological_processGO:0014012 peripheral nervous system axon regeneration ISS
 biological_processGO:0042246 tissue regeneration ISS
 biological_processGO:0042308 negative regulation of protein import into nucleus IDA
 biological_processGO:0042493 response to drug ISS
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation IDA
 biological_processGO:0048678 response to axon injury ISS
 biological_processGO:0051895 negative regulation of focal adhesion assembly IMP
 biological_processGO:0060588 negative regulation of lipoprotein lipid oxidation IDA
 biological_processGO:0071638 negative regulation of monocyte chemotactic protein-1 production IDA
 biological_processGO:1900016 negative regulation of cytokine production involved in inflammatory response IDA
 biological_processGO:2000098 negative regulation of smooth muscle cell-matrix adhesion IMP
 biological_processGO:2000405 negative regulation of T cell migration IDA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0022626 cytosolic ribosome ISS
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0043025 neuronal cell body ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005319 lipid transporter activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015485 cholesterol binding IDA
 molecular_functionGO:0036094 small molecule binding IEA


Pathways (from Reactome)
Pathway description
Transport of fatty acids


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000189058 APOD / P05090 / apolipoprotein D  / complex






 

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