ENSG00000213928


Homo sapiens

Features
Gene ID: ENSG00000213928
  
Biological name :IRF9
  
Synonyms : interferon regulatory factor 9 / IRF9 / Q00978
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q12
Gene start: 24161053
Gene end: 24166565
  
Corresponding Affymetrix probe sets: 203882_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454078
Ensembl peptide - ENSP00000454095
Ensembl peptide - ENSP00000313529
Ensembl peptide - ENSP00000380073
Ensembl peptide - ENSP00000453534
Ensembl peptide - ENSP00000453540
Ensembl peptide - ENSP00000453974
NCBI entrez gene - 10379     See in Manteia.
OMIM - 147574
RefSeq - NM_006084
RefSeq Peptide - NP_006075
swissprot - H0YNM9
swissprot - H0YNP4
swissprot - H7BXP4
swissprot - Q00978
swissprot - H0YMB0
swissprot - H0YMB6
Ensembl - ENSG00000213928
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 irf9ENSDARG00000016457Danio rerio
 Irf9ENSMUSG00000002325Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IRF4 / Q15306 / interferon regulatory factor 4ENSG0000013726533
IRF8 / Q02556 / interferon regulatory factor 8ENSG0000014096833
IRF5 / Q13568 / interferon regulatory factor 5ENSG0000012860426
IRF6 / O14896 / interferon regulatory factor 6ENSG0000011759526
IRF7 / Q92985 / interferon regulatory factor 7ENSG0000018550722
IRF3 / Q14653 / interferon regulatory factor 3ENSG0000012645619
IRF1 / P10914 / interferon regulatory factor 1ENSG0000012534715
IRF2 / P14316 / interferon regulatory factor 2ENSG0000016831013


Protein motifs (from Interpro)
Interpro ID Name
 IPR001346  Interferon regulatory factor DNA-binding domain
 IPR008984  SMAD/FHA domain superfamily
 IPR017855  SMAD-like domain superfamily
 IPR019471  Interferon regulatory factor-3
 IPR019817  Interferon regulatory factor, conserved site
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060333 interferon-gamma-mediated signaling pathway TAS
 biological_processGO:0060337 type I interferon signaling pathway TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001047 core promoter binding IMP
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA


Pathways (from Reactome)
Pathway description
Interferon gamma signaling
Interferon alpha/beta signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000170581 STAT2 / P52630 / signal transducer and activator of transcription 2  / complex / reaction
 ENSG00000115415 STAT1 / P42224 / signal transducer and activator of transcription 1  / complex / reaction






 

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