ENSG00000271447


Homo sapiens

Features
Gene ID: ENSG00000271447
  
Biological name :MMP28
  
Synonyms : matrix metallopeptidase 28 / MMP28 / Q9H239
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q12
Gene start: 35756249
Gene end: 35795707
  
Corresponding Affymetrix probe sets: 219909_at (Human Genome U133 Plus 2.0 Array)   222937_s_at (Human Genome U133 Plus 2.0 Array)   224207_x_at (Human Genome U133 Plus 2.0 Array)   239272_at (Human Genome U133 Plus 2.0 Array)   239273_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481051
Ensembl peptide - ENSP00000473853
Ensembl peptide - ENSP00000482385
Ensembl peptide - ENSP00000484562
Ensembl peptide - ENSP00000483539
Ensembl peptide - ENSP00000483299
NCBI entrez gene - 79148     See in Manteia.
OMIM - 608417
RefSeq - XM_017025064
RefSeq - XM_011525228
RefSeq - XM_011525229
RefSeq - XM_011525230
RefSeq - XM_011525231
RefSeq - XM_011525232
RefSeq - XM_017025061
RefSeq - XM_017025062
RefSeq - XM_017025063
RefSeq - NM_001032278
RefSeq - NM_024302
RefSeq - NM_032950
RefSeq - XM_011525225
RefSeq - XM_011525226
RefSeq - XM_011525227
RefSeq Peptide - NP_116568
RefSeq Peptide - NP_001027449
RefSeq Peptide - NP_077278
swissprot - C0H5X0
swissprot - A0A087WZ56
swissprot - Q9H239
swissprot - B3KV06
swissprot - A0A087X1Y9
Ensembl - ENSG00000271447
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mmp28ENSDARG00000059029Danio rerio
 MMP28ENSGALG00000002081Gallus gallus
 Mmp28ENSMUSG00000020682Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MMP19 / Q99542 / matrix metallopeptidase 19ENSG0000012334233
MMP9 / P14780 / matrix metallopeptidase 9ENSG0000010098528
MMP21 / Q8N119 / matrix metallopeptidase 21ENSG0000015448527
MMP2 / P08253 / matrix metallopeptidase 2ENSG0000008724527
MMP23B / O75900 / matrix metallopeptidase 23BENSG0000018940920
MMP26 / Q9NRE1 / matrix metallopeptidase 26ENSG0000016734616
Q96BH3 / ELSPBP1 / epididymal sperm binding protein 1ENSG000001693933


Protein motifs (from Interpro)
Interpro ID Name
 IPR000585  Hemopexin-like domain
 IPR001818  Peptidase M10, metallopeptidase
 IPR002477  Peptidoglycan binding-like
 IPR006026  Peptidase, metallopeptidase
 IPR018487  Hemopexin-like repeats
 IPR021190  Peptidase M10A
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR028735  Matrix metalloproteinase-28
 IPR033739  Peptidase M10A, catalytic domain
 IPR036365  PGBD-like superfamily
 IPR036375  Hemopexin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0010760 negative regulation of macrophage chemotaxis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031012 extracellular matrix IDA
 molecular_functionGO:0004222 metalloendopeptidase activity TAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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