ENSGALG00000000944


Gallus gallus

Features
Gene ID: ENSGALG00000000944
  
Biological name :SUPT4H1
  
Synonyms : SPT4 homolog, DSIF elongation factor subunit / SUPT4H1
  
Possible biological names infered from orthology : P63271 / P63272 / suppressor of Ty 4A / Supt4a
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 520176
Gene end: 523042
  
Corresponding Affymetrix probe sets: Gga.7978.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001392
NCBI entrez gene - 417470     See in Manteia.
RefSeq - NM_001257286
RefSeq Peptide - NP_001244215
swissprot - E1C4X4
Ensembl - ENSGALG00000000944
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6DGQ0ENSDARG00000113969Danio rerio
 P63272ENSG00000213246Homo sapiens
 P63271ENSMUSG00000020485Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009287  Transcription initiation Spt4
 IPR022800  Spt4/RpoE2 zinc finger
 IPR029040  RNA polymerase subunit RPABC4/transcription elongation factor Spt4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006325 chromatin organization IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0006397 mRNA processing IBA
 biological_processGO:0032785 negative regulation of DNA-templated transcription, elongation IEA
 biological_processGO:0032786 positive regulation of DNA-templated transcription, elongation IEA
 biological_processGO:0034243 regulation of transcription elongation from RNA polymerase II promoter IBA
 biological_processGO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0032044 DSIF complex IEA
 molecular_functionGO:0000993 RNA polymerase II core binding IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0003727 single-stranded RNA binding IBA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Transcription Elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000031461 CTDP1 / CTD phosphatase subunit 1 / Q7TSG2* / Q9Y5B0* / RNA polymerase II subunit A C-terminal domain phosphatase *  / reaction / complex
 ENSGALG00000006843 NCBP2 / A6PVI3* / NCBP2L* / P52298* / Q9CQ49* / nuclear cap binding protein subunit 2* / nuclear cap binding protein subunit 2 like*  / reaction / complex
 ENSGALG00000002087 NCBP1 / Q5ZJZ6 / Nuclear cap-binding protein subunit 1 / Q09161* / Q3UYV9*  / complex / reaction
 ENSGALG00000008532 NELFB / negative elongation factor complex member B / Q8WX92* / negative elongation factor B isoform 1 *  / complex
 ENSGALG00000039160 Q5ZI08 / SUPT5H / Transcription elongation factor SPT5 / Supt5* / O55201* / O00267* / SPT5 homolog, DSIF elongation factor subunit*  / reaction / complex






 

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