ENSGALG00000039160


Gallus gallus

Features
Gene ID: ENSGALG00000039160
  
Biological name :SUPT5H
  
Synonyms : Q5ZI08 / SUPT5H / Transcription elongation factor SPT5
  
Possible biological names infered from orthology : O00267 / O55201 / SPT5 homolog, DSIF elongation factor subunit / Supt5
  
Species: Gallus gallus
  
Chr. number: 32
Strand: 1
Band:
Gene start: 53577
Gene end: 61181
  
Corresponding Affymetrix probe sets: Gga.7037.1.S1_s_at (Chicken Array)   Gga.7037.2.S1_s_at (Chicken Array)   GgaAffx.9263.1.S1_s_at (Chicken Array)   GgaAffx.9264.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047967
Ensembl peptide - ENSGALP00000047895
NCBI entrez gene - 426493     See in Manteia.
RefSeq - XM_015300211
RefSeq - NM_001031384
RefSeq Peptide - NP_001026555
swissprot - Q5ZI08
swissprot - A0A1D5P5C8
Ensembl - ENSGALG00000039160
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 supt5hENSDARG00000042724Danio rerio
 O00267ENSG00000196235Homo sapiens
 Supt5ENSMUSG00000003435Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005100  Transcription elongation factor Spt5, NGN domain
 IPR005824  KOW
 IPR006645  NusG, N-terminal
 IPR008991  Translation protein SH3-like domain superfamily
 IPR014722  Ribosomal protein L2, domain 2
 IPR017071  Transcription elongation factor Spt5
 IPR022581  Spt5 transcription elongation factor, N-terminal
 IPR024945  Spt5 C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0006397 mRNA processing IBA
 biological_processGO:0016239 positive regulation of macroautophagy IEA
 biological_processGO:0032784 regulation of DNA-templated transcription, elongation IEA
 biological_processGO:0032785 negative regulation of DNA-templated transcription, elongation IEA
 biological_processGO:0032786 positive regulation of DNA-templated transcription, elongation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:1900364 negative regulation of mRNA polyadenylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0032044 DSIF complex IEA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003729 mRNA binding IBA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
RNA Polymerase II Transcription Elongation
RNA Pol II CTD phosphorylation and interaction with CE


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008532 NELFB / negative elongation factor complex member B / Q8WX92* / negative elongation factor B isoform 1 *  / complex
 ENSGALG00000000944 SUPT4H1 / SPT4 homolog, DSIF elongation factor subunit / P63272* / Supt4a* / P63271* / suppressor of Ty 4A*  / reaction / complex
 ENSGALG00000006843 NCBP2 / A6PVI3* / NCBP2L* / P52298* / Q9CQ49* / nuclear cap binding protein subunit 2* / nuclear cap binding protein subunit 2 like*  / complex / reaction
 ENSGALG00000031461 CTDP1 / CTD phosphatase subunit 1 / Q7TSG2* / Q9Y5B0* / RNA polymerase II subunit A C-terminal domain phosphatase *  / reaction / complex
 ENSGALG00000016974 GTF2F2 / general transcription factor IIF subunit 2 / P13984* / Q8R0A0* / ral transcription factor IIF subunit 2 *  / reaction
 ENSGALG00000015787 RNGTT / RNA guanylyltransferase and 5-phosphatase / O55236* / O60942*  / reaction
 ENSGALG00000002087 NCBP1 / Q5ZJZ6 / Nuclear cap-binding protein subunit 1 / Q09161* / Q3UYV9*  / reaction / complex
 ENSGALG00000013889 RNMT / RNA guanine-7 methyltransferase / O43148* / Q9D0L8*  / reaction






 

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