ENSGALG00000002087


Gallus gallus

Features
Gene ID: ENSGALG00000002087
  
Biological name :NCBP1
  
Synonyms : NCBP1 / Nuclear cap-binding protein subunit 1 / Q5ZJZ6
  
Possible biological names infered from orthology : Q09161 / Q3UYV9
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 70739406
Gene end: 70771390
  
Corresponding Affymetrix probe sets: Gga.2984.1.S1_at (Chicken Array)   GgaAffx.12391.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000061075
Ensembl peptide - ENSGALP00000003250
NCBI entrez gene - 427379     See in Manteia.
RefSeq - NM_001031440
RefSeq Peptide - NP_001026611
swissprot - Q5ZJZ6
swissprot - A0A1L1RQK9
Ensembl - ENSGALG00000002087
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NCBP1ENSG00000136937Homo sapiens
 Ncbp1ENSMUSG00000028330Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003890  MIF4G-like, type 3
 IPR015172  MIF4G-like, type 1
 IPR015174  MIF4G-like, type 2
 IPR016021  MIF4G-like domain superfamily
 IPR016024  Armadillo-type fold
 IPR027159  Nuclear cap-binding protein subunit 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ISS
 biological_processGO:0000245 spliceosomal complex assembly IEA
 biological_processGO:0000398 mRNA splicing, via spliceosome IBA
 biological_processGO:0006370 7-methylguanosine mRNA capping ISS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006406 mRNA export from nucleus IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006446 regulation of translational initiation IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0016070 RNA metabolic process IEA
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0031053 primary miRNA processing IBA
 biological_processGO:0031442 positive regulation of mRNA 3"-end processing IEA
 biological_processGO:0045292 mRNA cis splicing, via spliceosome IEA
 biological_processGO:0048026 positive regulation of mRNA splicing, via spliceosome IEA
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0098789 pre-mRNA cleavage required for polyadenylation IEA
 biological_processGO:1905216 positive regulation of RNA binding IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005845 mRNA cap binding complex IEA
 cellular_componentGO:0005846 nuclear cap binding complex IEA
 cellular_componentGO:0034518 RNA cap binding complex IEA
 molecular_functionGO:0000339 RNA cap binding IEA
 molecular_functionGO:0000340 RNA 7-methylguanosine cap binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IBA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
SLBP independent Processing of Histone Pre-mRNAs
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Transport of Mature mRNA derived from an Intron-Containing Transcript
snRNP Assembly
RNA Polymerase II Pre-transcription Events
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
mRNA 3-end processing
Processing of Capped Intron-Containing Pre-mRNA
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Processing of Intronless Pre-mRNAs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000944 SUPT4H1 / SPT4 homolog, DSIF elongation factor subunit / P63272* / Supt4a* / P63271* / suppressor of Ty 4A*  / complex / reaction
 ENSGALG00000001962 PTBP1 / polypyrimidine tract-binding protein 1 / P26599*  / reaction / complex
 ENSGALG00000016974 GTF2F2 / general transcription factor IIF subunit 2 / P13984* / Q8R0A0* / ral transcription factor IIF subunit 2 *  / complex / reaction
 ENSGALG00000006843 NCBP2 / A6PVI3* / NCBP2L* / P52298* / Q9CQ49* / nuclear cap binding protein subunit 2* / nuclear cap binding protein subunit 2 like*  / reaction / complex
 ENSGALG00000011863 POLDIP3 / DNA polymerase delta interacting protein 3 / Q8BG81* / Q9BY77* / Mus musculus polymerase (DNA-directed), delta interacting protein 3 (Poldip3), transcript variant 2, mRNA.*  / complex
 ENSGALG00000015712 SLBP / stem-loop binding protein / P97440* / Q14493*  / reaction / complex
 ENSGALG00000008520 EIF4G1 / eukaryotic translation initiation factor 4 gamma 1 / Q04637* / Q6NZJ6*  / complex
 ENSGALG00000008532 NELFB / negative elongation factor complex member B / Q8WX92* / negative elongation factor B isoform 1 *  / complex
 ENSGALG00000006760 CSTF2 / Q9H0L4* / CSTF2T* / Q8BIQ5* / Q8C7E9* / P33240* / cleavage stimulation factor subunit 2* / cleavage stimulation factor subunit 2 tau variant*  / complex / reaction
 ENSGALG00000012000 Q5ZK35 / METTL14 / N6-adenosine-methyltransferase non-catalytic subunit / Q3UIK4* / Q9HCE5* / methyltransferase like 14*  / reaction
 ENSGALG00000011685 CSTF3 / cleavage stimulation factor subunit 3 / Q12996* / Q99LI7*  / reaction / complex
 ENSGALG00000011660 WTAP / WT1 associated protein / Q15007* / Q9ER69* / Wilms tumour 1-associating protein*  / reaction
 ENSGALG00000042011 HNRNPA1 / Gallus gallus heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1), mRNA. / Q32P51* / P49312* / P09651* / HNRNPA1L2* / HNRNPA1P48* / heterogeneous nuclear ribonucleoprotein A1* / ...  / complex / reaction
 ENSGALG00000039160 Q5ZI08 / SUPT5H / Transcription elongation factor SPT5 / Supt5* / O55201* / O00267* / SPT5 homolog, DSIF elongation factor subunit*  / complex / reaction
 ENSGALG00000031461 CTDP1 / CTD phosphatase subunit 1 / Q7TSG2* / Q9Y5B0* / RNA polymerase II subunit A C-terminal domain phosphatase *  / reaction / complex






 

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