ENSGALG00000001962


Gallus gallus

Features
Gene ID: ENSGALG00000001962
  
Biological name :PTBP1
  
Synonyms : polypyrimidine tract-binding protein 1 / PTBP1
  
Possible biological names infered from orthology : P26599
  
Species: Gallus gallus
  
Chr. number: 28
Strand: 1
Band:
Gene start: 2817697
Gene end: 2846212
  
Corresponding Affymetrix probe sets: Gga.3150.1.S1_at (Chicken Array)   GgaAffx.25338.4.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045043
Ensembl peptide - ENSGALP00000064597
Ensembl peptide - ENSGALP00000060866
Ensembl peptide - ENSGALP00000055533
Ensembl peptide - ENSGALP00000003035
NCBI entrez gene - 420098     See in Manteia.
RefSeq - XM_015299922
RefSeq - NM_001030935
RefSeq - XM_015299920
RefSeq - XM_015299921
RefSeq Peptide - NP_001026106
swissprot - A0A1L1S0D8
swissprot - A0A1L1RPZ0
swissprot - A0A1D5PRK6
swissprot - F1P5K0
Ensembl - ENSGALG00000001962
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptbp1aENSDARG00000019362Danio rerio
 ptbp1bENSDARG00000031907Danio rerio
 PTBP1ENSG00000011304Homo sapiens
 Ptbp1ENSMUSG00000006498Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTBP2 / polypyrimidine tract binding protein 2 / Q91Z31* / Q9UKA9*ENSGALG0000000555272
PTBP3 / polypyrimidine tract binding protein 3 / O95758* / Q8BHD7*ENSGALG0000001566962
HNRNPLL / heterogeneous nuclear ribonucleoprotein L-like / Q8WVV9* / Q921F4* / Heteroous nuclear ribonucleoprotein L-like *ENSGALG0000000850425
Hnrnpl* / Q8R081* / AC008982.1* / Heteroous nuclear ribonucleoprotein L *ENSGALG0000004392911


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR006536  HnRNP-L/PTB
 IPR012677  Nucleotide-binding alpha-beta plait domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0033119 negative regulation of RNA splicing IEA
 biological_processGO:0048025 negative regulation of mRNA splicing, via spliceosome IEA
 biological_processGO:0051148 negative regulation of muscle cell differentiation IEA
 biological_processGO:0075522 IRES-dependent viral translational initiation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0036002 pre-mRNA binding IEA


Pathways (from Reactome)
Pathway description
FGFR2 alternative splicing
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002087 NCBP1 / Q5ZJZ6 / Nuclear cap-binding protein subunit 1 / Q09161* / Q3UYV9*  / reaction / complex
 ENSGALG00000006843 NCBP2 / A6PVI3* / NCBP2L* / P52298* / Q9CQ49* / nuclear cap binding protein subunit 2* / nuclear cap binding protein subunit 2 like*  / reaction / complex
 ENSGALG00000016974 GTF2F2 / general transcription factor IIF subunit 2 / P13984* / Q8R0A0* / ral transcription factor IIF subunit 2 *  / reaction / complex
 ENSGALG00000042011 HNRNPA1 / Gallus gallus heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1), mRNA. / Q32P51* / P49312* / P09651* / HNRNPA1L2* / HNRNPA1P48* / heterogeneous nuclear ribonucleoprotein A1* / ...  / complex / reaction






 

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