ENSDARG00000019362


Danio rerio

Features
Gene ID: ENSDARG00000019362
  
Biological name :ptbp1a
  
Synonyms : polypyrimidine tract binding protein 1a / ptbp1a
  
Possible biological names infered from orthology : P26599 / polypyrimidine tract binding protein 1 / PTBP1
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 26288301
Gene end: 26300619
  
Corresponding Affymetrix probe sets: Dr.20803.1.S1_at (Zebrafish Array)   Dr.20803.2.S1_at (Zebrafish Array)   Dr.5460.1.A1_at (Zebrafish Array)   NM_001020477_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000011705
NCBI entrez gene - 323490     See in Manteia.
RefSeq - XM_021478816
RefSeq - NM_001020477
RefSeq Peptide - NP_001018313
swissprot - Q503D3
ZFIN ID - ZDB-GENE-050522-492
Ensembl - ENSDARG00000019362
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTBP1ENSGALG00000001962Gallus gallus
 PTBP1ENSG00000011304Homo sapiens
 Ptbp1ENSMUSG00000006498Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptbp1b / polypyrimidine tract binding protein 1b / PTBP1* / P26599* / polypyrimidine tract binding protein 1*ENSDARG0000003190784
ptbp3 / polypyrimidine tract binding protein 3 / O95758* / Q8BHD7*ENSDARG0000004375767
ptbp2b / polypyrimidine tract binding protein 2b / PTBP2* / Q91Z31* / Q9UKA9* / polypyrimidine tract binding protein 2*ENSDARG0000001590163
ptbp2a / polypyrimidine tract binding protein 2a / PTBP2* / Q91Z31* / Q9UKA9* / polypyrimidine tract binding protein 2*ENSDARG0000010194761
hnrnpl / heterogeneous nuclear ribonucleoprotein L / Q8R081* / P14866* / AC008982.1* / Heteroous nuclear ribonucleoprotein L *ENSDARG0000003532424
hnrnpl2 / heterogeneous nuclear ribonucleoprotein L2 / Q8R081* / P14866* / HNRNPL* / AC008982.1* / Heteroous nuclear ribonucleoprotein L * / heterogeneous nuclear ribonucleoprotein L*ENSDARG0000005930324
CABZ01100304.1 / Q8WVV9* / HNRNPLL* / heterogeneous nuclear ribonucleoprotein L like*ENSDARG0000011610110


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR033110  ROD1, RNA recognition motif 4
 IPR034798  Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2
 IPR035000  PTBP1, RNA recognition motif 1
 IPR035001  PTBP1, RNA recognition motif 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0045595 regulation of cell differentiation IEA
 biological_processGO:0045746 negative regulation of Notch signaling pathway IMP
 biological_processGO:0060472 positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration IMP
 biological_processGO:0060729 intestinal epithelial structure maintenance IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA


Pathways (from Reactome)
Pathway description
FGFR2 alternative splicing
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000084 yolk yolk opaque , abnormal
Show

 ZFA:0000093 blastomere blastomere microtubule disorganized , abnormal
Show

 ZFA:0000329 chorion chorion soft , abnormal
Show

 ZFA:0000541 marginal blastomere marginal blastomere microtubule disorganized , abnormal
marginal blastomere microtubule sparse , abnormal
Show

 ZFA:0001076 intestinal bulb intestinal bulb lacks parts or has fewer parts of type intestinal villus , abnormal
intestinal bulb muscle degenerate , abnormal
Show

 ZFA:0001094 whole organism whole organism wholly ventralized , abnormal
Show

 ZFA:0001175 blastodisc blastodisc decreased size , abnormal
Show

 ZFA:0001323 mid intestine mid intestine intestinal villus increased circumference , abnormal
mid intestine muscle degenerate , abnormal
Show

 ZFA:0005126 intestinal bulb epithelium intestinal bulb epithelium intestinal villus increased circumference , abnormal
intestinal bulb epithelium goblet cell decreased amount , abnormal
Show

 ZFA:0005127 mid intestine epithelium mid intestine epithelium goblet cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr