ENSGALG00000002886


Gallus gallus

Features
Gene ID: ENSGALG00000002886
  
Biological name :NKX2-5
  
Synonyms : homeobox protein Nkx-2.5 / NKX2-5
  
Possible biological names infered from orthology :
  
Species: Gallus gallus
  
Chr. number: 13
Strand: -1
Band:
Gene start: 9204062
Gene end: 9206276
  
Corresponding Affymetrix probe sets: Gga.638.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004542
NCBI entrez gene - 396073     See in Manteia.
RefSeq - NM_205164
RefSeq Peptide - NP_990495
swissprot - F1NC42
Ensembl - ENSGALG00000002886
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nkx2.5ENSDARG00000018004Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NKX2-3 / NK2 homeobox 3 / P97334* / Q8TAU0* / Homeobox protein Nkx-2.3 *ENSGALG0000003093251
NKX2-6 / homeobox protein Nkx-2.6 ENSGALG0000000036537
NKX2-1 / homeobox protein Nkx-2.1 ENSGALG0000003763232
NKX2-2 / NK2 homeobox 2 / O95096* / P42586*ENSGALG0000003686930
NKX2-4 / NK2 homeobox 4 / Q9EQM3* / Q9H2Z4* / Homeobox protein Nkx-2.4 *ENSGALG0000003583528
NKX2-8 / NK2 homeobox 8 / Nkx2-9* / O15522* / O70584* / Homeobox protein Nkx-2.8 *ENSGALG0000002848325
NKX3-2 / homeobox protein Nkx-3.2 / P78367* / P97503* / NK3 homeobox 2*ENSGALG0000003185924
HMX1 / homeobox protein HMX1 ENSGALG0000004206220
HMX3 / homeobox protein HMX3 / A6NHT5* / P42581* / H6 family homeobox 3*ENSGALG0000002341520
HMX2 / H6 family homeobox 2 / A2RU54* / P43687* / Homeobox protein HMX2 *ENSGALG0000003087518
SOHO-1 / sensory organ homeobox protein SOHo / HMX1* / O70218* / Q9NP08* / H6 family homeobox 1* / Homeobox protein HMX1 *ENSGALG0000001559916


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa
 IPR033629  Homeobox protein NKX-2.5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0060048 cardiac muscle contraction IEA
 biological_processGO:0071772 response to BMP IDA
 biological_processGO:1903779 regulation of cardiac conduction IEA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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