ENSGALG00000031859


Gallus gallus

Features
Gene ID: ENSGALG00000031859
  
Biological name :NKX3-2
  
Synonyms : homeobox protein Nkx-3.2 / NKX3-2
  
Possible biological names infered from orthology : NK3 homeobox 2 / P78367 / P97503
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 77992024
Gene end: 77993970
  
Corresponding Affymetrix probe sets: Gga.70.1.S1_at (Chicken Array)   Gga.9446.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053034
Ensembl peptide - ENSGALP00000064633
Ensembl peptide - ENSGALP00000053539
NCBI entrez gene - 373932     See in Manteia.
RefSeq - NM_204137
RefSeq Peptide - NP_989468
swissprot - A0A1L1S0G9
swissprot - A0A1D5PL25
swissprot - A0A1D5PJN8
Ensembl - ENSGALG00000031859
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nkx3.2ENSDARG00000037639Danio rerio
 NKX3-2ENSG00000109705Homo sapiens
 Nkx3-2ENSMUSG00000049691Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NKX2-3 / NK2 homeobox 3 / P97334* / Q8TAU0* / Homeobox protein Nkx-2.3 *ENSGALG0000003093229
HMX1 / homeobox protein HMX1 ENSGALG0000004206228
HMX3 / homeobox protein HMX3 / A6NHT5* / P42581* / H6 family homeobox 3*ENSGALG0000002341527
NKX2-5 / homeobox protein Nkx-2.5 ENSGALG0000000288625
NKX2-2 / NK2 homeobox 2 / O95096* / P42586*ENSGALG0000003686924
NKX2-1 / homeobox protein Nkx-2.1 ENSGALG0000003763224
HMX2 / H6 family homeobox 2 / A2RU54* / P43687* / Homeobox protein HMX2 *ENSGALG0000003087523
NKX2-6 / homeobox protein Nkx-2.6 ENSGALG0000000036522
NKX2-4 / NK2 homeobox 4 / Q9EQM3* / Q9H2Z4* / Homeobox protein Nkx-2.4 *ENSGALG0000003583522
NKX2-8 / NK2 homeobox 8 / Nkx2-9* / O15522* / O70584* / Homeobox protein Nkx-2.8 *ENSGALG0000002848321
SOHO-1 / sensory organ homeobox protein SOHo / HMX1* / O70218* / Q9NP08* / H6 family homeobox 1* / Homeobox protein HMX1 *ENSGALG0000001559919


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007368 determination of left/right symmetry IEA
 biological_processGO:0031016 pancreas development IEA
 biological_processGO:0032331 negative regulation of chondrocyte differentiation IEA
 biological_processGO:0042474 middle ear morphogenesis IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0048513 animal organ development IEA
 biological_processGO:0048536 spleen development IEA
 biological_processGO:0048645 animal organ formation IEA
 biological_processGO:0048705 skeletal system morphogenesis IEA
 biological_processGO:0048706 embryonic skeletal system development IEA
 biological_processGO:0055123 digestive system development IEA
 biological_processGO:0060576 intestinal epithelial cell development IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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