ENSGALG00000003359


Gallus gallus

Features
Gene ID: ENSGALG00000003359
  
Biological name :RAB5C
  
Synonyms : Q98932 / RAB5C / Ras-related protein Rab-5C
  
Possible biological names infered from orthology : P35278 / P51148 / RAB5C, member RAS oncogene family
  
Species: Gallus gallus
  
Chr. number: 27
Strand: -1
Band:
Gene start: 5260325
Gene end: 5272254
  
Corresponding Affymetrix probe sets: Gga.2500.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005302
Ensembl peptide - ENSGALP00000045206
NCBI entrez gene - 395197     See in Manteia.
RefSeq - NM_204525
RefSeq - XM_015299568
RefSeq Peptide - NP_989856
swissprot - Q98932
Ensembl - ENSGALG00000003359
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab5cENSDARG00000026712Danio rerio
 RAB5CENSG00000108774Homo sapiens
 Rab5cENSMUSG00000019173Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAB5A / RAB5A, member RAS oncogene family / P20339* / Q9CQD1* / Ras-related protein Rab-5A *ENSGALG0000001127288
RAB5B / ras-related protein Rab-5B / P61020* / P61021* / RAB5B, member RAS oncogene family*ENSGALG0000004248273
RAB17 / RAB17, member RAS oncogene family / P35292* / Q9H0T7* / Ras-related protein Rab-17 *ENSGALG0000000389946
RAB22A / RAB22A, member RAS oncogene family / P35285* / Q9UL26*ENSGALG0000000755444
RAB31 / RAB31, member RAS oncogene family / Q13636*ENSGALG0000002287443
RAB21 / RAB21, member RAS oncogene family / P35282* / Q9UL25*ENSGALG0000001018340
RAB20 / RAB20, member RAS oncogene family / P35295* / Q9NX57* / Ras-related protein Rab-20 *ENSGALG0000001684431
Q6IMM1 / DNAJC27 / DnaJ homolog subfamily C member 27 / Q8CFP6* / Q9NZQ0* / DnaJ heat shock protein family (Hsp40) member C27*ENSGALG0000002896727


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0030100 regulation of endocytosis IBA
 biological_processGO:0048227 plasma membrane to endosome transport IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IBA
 cellular_componentGO:0005811 lipid droplet IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030139 endocytic vesicle IBA
 cellular_componentGO:0031901 early endosome membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019003 GDP binding ISS


Pathways (from Reactome)
Pathway description
Golgi Associated Vesicle Biogenesis
Neutrophil degranulation
TBC/RABGAPs
Clathrin-mediated endocytosis
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000021611 Q9JM13* / Q9UJ41* / RABGEF1* / AC027644.4* / Rab5 GDP/GTP exchange factor * / RAB guanine nucleotide exchange factor 1*  / complex
 ENSGALG00000006140 GGA2 / golgi associated, gamma adaptin ear containing, ARF binding protein 2 / Q6P5E6* / Q9UJY4* / ADP-ribosylation factor-binding protein GGA2 *  / complex
 ENSGALG00000039658 GGA1 / golgi associated, gamma adaptin ear containing, ARF binding protein 1 / Q8R0H9* / Q9UJY5* / ADP-ribosylation factor-binding protein GGA1 *  / complex
 ENSGALG00000039221 A6NDS4* / B9A6J9* / TBC1D3* / P0C7X1* / Q2M2D7* / Q6DHY5* / Q6IPX1* / Q8IZP1* / Q86UD7* / TBC1D3F* / TBC1D3H* / TBC1D3G* / TBC1D3I* / TBC1D3K* / TBC1D3L* / TBC1D26* / TBC1D28* / TBC1D3B* / ...  / complex / reaction






 

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