ENSGALG00000004435


Gallus gallus

Features
Gene ID: ENSGALG00000004435
  
Biological name :RAB27A
  
Synonyms : RAB27A / RAB27A, member RAS oncogene family
  
Possible biological names infered from orthology : P51159 / Q9ERI2
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 7968909
Gene end: 7999976
  
Corresponding Affymetrix probe sets: GgaAffx.20431.1.S1_at (Chicken Array)   GgaAffx.2750.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000007047
Ensembl peptide - ENSGALP00000048603
Ensembl peptide - ENSGALP00000045451
NCBI entrez gene - 415410     See in Manteia.
RefSeq - NM_001168705
RefSeq Peptide - NP_001162176
swissprot - D2D3P4
swissprot - A0A1D5P7B6
Ensembl - ENSGALG00000004435
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab27aENSDARG00000103935Danio rerio
 P51159ENSG00000069974Homo sapiens
 Q9ERI2ENSMUSG00000032202Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAB3C / RAB3C, member RAS oncogene family / P62823* / Q96E17*ENSGALG0000001472641
RAB8B / RAB8B, member RAS oncogene family / P61028* / Q92930*ENSGALG0000000348739
RAB8A / Q5F470 / Ras-related protein Rab-8A / P61006* / P55258* / RAB8A, member RAS oncogene family*ENSGALG0000002885138
RAB3A / RAB3A, member RAS oncogene family / P20336* / P63011*ENSGALG0000003006838
RAB10 / ras-related protein Rab-10 / P61026* / P61027* / RAB10, member RAS oncogene family*ENSGALG0000001653537
RASEF / RAS and EF-hand domain containing / Q5RI75* / Q8IZ41* / Ras and EF-hand domain-containing protein homolog *ENSGALG0000001257634
RAB12 / RAB12, member RAS oncogene family / P35283* / Q6IQ22* / Ras-related protein Rab-12 *ENSGALG0000003360832
RAB44 / RAB44, member RAS oncogene family / Q8CB87* / Ras-related protein Rab-44 *ENSGALG0000000054432
RAB3B / RAB3B, member RAS oncogene family / P20337* / Q9CZT8*ENSGALG0000001056732
ENSGALG0000001518329
ENSGALG0000004648828


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006605 protein targeting IEA
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0019882 antigen processing and presentation IEA
 biological_processGO:0030318 melanocyte differentiation IEA
 biological_processGO:0032400 melanosome localization IEA
 biological_processGO:0032402 melanosome transport IEA
 biological_processGO:0036257 multivesicular body organization IEA
 biological_processGO:0043316 cytotoxic T cell degranulation IEA
 biological_processGO:0043320 natural killer cell degranulation IEA
 biological_processGO:0043473 pigmentation IEA
 biological_processGO:0045921 positive regulation of exocytosis IEA
 biological_processGO:0050766 positive regulation of phagocytosis IEA
 biological_processGO:0051875 pigment granule localization IEA
 biological_processGO:0051904 pigment granule transport IEA
 biological_processGO:0071985 multivesicular body sorting pathway IEA
 biological_processGO:0097278 complement-dependent cytotoxicity IEA
 biological_processGO:1903307 positive regulation of regulated secretory pathway IEA
 biological_processGO:1903428 positive regulation of reactive oxygen species biosynthetic process IEA
 biological_processGO:1903435 positive regulation of constitutive secretory pathway IEA
 biological_processGO:1990182 exosomal secretion IEA
 cellular_componentGO:0001750 photoreceptor outer segment IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0030141 secretory granule IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0032585 multivesicular body membrane IEA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0070382 exocytic vesicle IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019003 GDP binding IEA
 molecular_functionGO:0031489 myosin V binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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