Manteia

ENSDARG00000103935

Danio rerio

Features

Gene ID:	ENSDARG00000103935

Biological name :	rab27a

Synonyms :	rab27a / RAB27A, member RAS oncogene family

Possible biological names infered from orthology :	P51159 / Q9ERI2

Species:	Danio rerio

Chr. number:	18
Strand:	1
Band:
Gene start:	2228737
Gene end:	2266585

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000133424 NCBI entrez gene - 570907 See in Manteia. RefSeq - NM_001030257 RefSeq Peptide - NP_001025428 swissprot - Q4V8U8 ZFIN ID - ZDB-GENE-050913-46 Ensembl - ENSDARG00000103935

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
RAB27A	ENSGALG00000004435	Gallus gallus
P51159	ENSG00000069974	Homo sapiens
Q9ERI2	ENSMUSG00000032202	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
rab27b / RAB27B, member RAS oncogene family / O00194* / Q99P58*	ENSDARG00000087762	68
rab3c / RAB3C, member RAS oncogene family	ENSDARG00000014462	43
rab3ab / RAB3A, member RAS oncogene family, b / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*	ENSDARG00000043835	42
rab3aa / RAB3A, member RAS oncogene family, a / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*	ENSDARG00000056347	41
rab3da / RAB3D, member RAS oncogene family, a / RAB3D* / P35276* / O95716* / RAB3D, member RAS oncogene family*	ENSDARG00000018107	41
rab3b / RAB3B, member RAS oncogene family / RAB3C* / Q9CZT8* / P20337* / P62823* / Q96E17* / RAB3C, member RAS oncogene family*	ENSDARG00000114797	41
rab3db / RAB3D, member RAS oncogene family, b / RAB3D* / P35276* / O95716* / RAB3D, member RAS oncogene family*	ENSDARG00000101534	41
rab8b / RAB8B, member RAS oncogene family / P61028* / Q92930*	ENSDARG00000068628	38
rab8a / RAB8A, member RAS oncogene family / P55258* / P61006*	ENSDARG00000067920	37
megf8 / multiple EGF-like-domains 8	ENSDARG00000103934	36
rab10 / RAB10, member RAS oncogene family / P61026*	ENSDARG00000046106	35
rab15 / RAB15, member RAS oncogene family / P59190*	ENSDARG00000026484	34
rab13 / Q7T3A4 / RAB13, member RAS oncogene family / Q9DD03* / P51153* / Ras-related protein Rab-13 *	ENSDARG00000034771	34
rab12 / RAB12, member RAS oncogene family / Q6IQ22*	ENSDARG00000089428	33
A5WW21 / zgc:162879	ENSDARG00000074163	33
rasef / RAS and EF-hand domain containing / Q5RI75* / Q8IZ41* / Ras and EF-hand domain-containing protein homolog *	ENSDARG00000076250	32
rab44 / RAB44, member RAS oncogene family / Q8CB87* / Ras-related protein Rab-44 *	ENSDARG00000028389	29

Protein motifs (from Interpro)

Interpro ID	Name
IPR001806	Small GTPase superfamily
IPR005225	Small GTP-binding protein domain
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0032402	melanosome transport	IBA
biological_process	GO:0045921	positive regulation of exocytosis	IBA
cellular_component	GO:0030141	secretory granule	IBA
cellular_component	GO:0042470	melanosome	IBA
molecular_function	GO:0003924	GTPase activity	IEA
molecular_function	GO:0005525	GTP binding	IEA

Pathways (from Reactome)

Pathway description

Neutrophil degranulation

RAB geranylgeranylation

RAB GEFs exchange GTP for GDP on RABs

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000056122	gdi1 / GDP dissociation inhibitor 1 / P31150* / P50396* / Rab GDP dissociation inhibitor alpha *	/ complex

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr