Manteia

ENSDARG00000068628

Danio rerio

Features

Gene ID:	ENSDARG00000068628

Biological name :	rab8b

Synonyms :	rab8b / RAB8B, member RAS oncogene family

Possible biological names infered from orthology :	P61028 / Q92930

Species:	Danio rerio

Chr. number:	7
Strand:	1
Band:
Gene start:	29301497
Gene end:	29310861

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000090100 NCBI entrez gene - 100093706 See in Manteia. swissprot - A5PLC7 ZFIN ID - ZDB-GENE-070620-16 Ensembl - ENSDARG00000068628

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
RAB8B	ENSGALG00000003487	Gallus gallus
RAB8B	ENSG00000166128	Homo sapiens
Rab8b	ENSMUSG00000036943	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
rab8a / RAB8A, member RAS oncogene family / P55258* / P61006*	ENSDARG00000067920	82
megf8 / multiple EGF-like-domains 8	ENSDARG00000103934	78
rab10 / RAB10, member RAS oncogene family / P61026*	ENSDARG00000046106	66
rab13 / Q7T3A4 / RAB13, member RAS oncogene family / Q9DD03* / P51153* / Ras-related protein Rab-13 *	ENSDARG00000034771	64
rab15 / RAB15, member RAS oncogene family / P59190*	ENSDARG00000026484	47
rab3aa / RAB3A, member RAS oncogene family, a / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*	ENSDARG00000056347	46
rab3c / RAB3C, member RAS oncogene family	ENSDARG00000014462	46
rab3da / RAB3D, member RAS oncogene family, a / RAB3D* / P35276* / O95716* / RAB3D, member RAS oncogene family*	ENSDARG00000018107	44
rab3ab / RAB3A, member RAS oncogene family, b / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*	ENSDARG00000043835	44
rab3b / RAB3B, member RAS oncogene family / RAB3C* / Q9CZT8* / P20337* / P62823* / Q96E17* / RAB3C, member RAS oncogene family*	ENSDARG00000114797	43
rab3db / RAB3D, member RAS oncogene family, b / RAB3D* / P35276* / O95716* / RAB3D, member RAS oncogene family*	ENSDARG00000101534	42
rab27a / RAB27A, member RAS oncogene family / P51159*	ENSDARG00000103935	41
rab12 / RAB12, member RAS oncogene family / Q6IQ22*	ENSDARG00000089428	41
rab27b / RAB27B, member RAS oncogene family / O00194* / Q99P58*	ENSDARG00000087762	40
A5WW21 / zgc:162879	ENSDARG00000074163	38
rab44 / RAB44, member RAS oncogene family / Q8CB87* / Ras-related protein Rab-44 *	ENSDARG00000028389	37
rasef / RAS and EF-hand domain containing / Q5RI75* / Q8IZ41* / Ras and EF-hand domain-containing protein homolog *	ENSDARG00000076250	35

Protein motifs (from Interpro)

Interpro ID	Name
IPR001806	Small GTPase superfamily
IPR005225	Small GTP-binding protein domain
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006904	vesicle docking involved in exocytosis	IBA
biological_process	GO:0009306	protein secretion	IBA
biological_process	GO:0017157	regulation of exocytosis	IBA
biological_process	GO:0060828	regulation of canonical Wnt signaling pathway	IMP
biological_process	GO:0072659	protein localization to plasma membrane	IBA
cellular_component	GO:0005768	endosome	IBA
cellular_component	GO:0005886	plasma membrane	IBA
cellular_component	GO:0008021	synaptic vesicle	IBA
cellular_component	GO:0030667	secretory granule membrane	IBA
molecular_function	GO:0003924	GTPase activity	IEA
molecular_function	GO:0005525	GTP binding	IEA

Pathways (from Reactome)

Pathway description

TBC/RABGAPs

RAB geranylgeranylation

RAB GEFs exchange GTP for GDP on RABs

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000005927	tbc1d17 / TBC1 domain family, member 17 / Q8BYH7* / Q9HA65*	/ complex / reaction

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr