Manteia

ENSDARG00000089428

Danio rerio

Features

Gene ID:	ENSDARG00000089428

Biological name :	rab12

Synonyms :	rab12 / RAB12, member RAS oncogene family

Possible biological names infered from orthology :	P35283 / Q6IQ22 / Ras-related protein Rab-12

Species:	Danio rerio

Chr. number:	2
Strand:	1
Band:
Gene start:	54387710
Gene end:	54423636

Corresponding Affymetrix probe sets:	Dr.15011.1.A1_at (Zebrafish Array) Dr.15011.2.S1_at (Zebrafish Array) NM_001020630_at (Zebrafish Genome Array with custom cdf files)

Cross references:	Ensembl peptide - ENSDARP00000110018 Ensembl peptide - ENSDARP00000154059 NCBI entrez gene - 553657 See in Manteia. RefSeq - NM_001020630 RefSeq Peptide - NP_001018466 swissprot - Q502Q0 ZFIN ID - ZDB-GENE-050522-555 Ensembl - ENSDARG00000089428

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
RAB12	ENSGALG00000033608	Gallus gallus
RAB12	ENSG00000206418	Homo sapiens
Rab12	ENSMUSG00000023460	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
rab3da / RAB3D, member RAS oncogene family, a / RAB3D* / P35276* / O95716* / RAB3D, member RAS oncogene family*	ENSDARG00000018107	41
rab3db / RAB3D, member RAS oncogene family, b / RAB3D* / P35276* / O95716* / RAB3D, member RAS oncogene family*	ENSDARG00000101534	40
rab10 / RAB10, member RAS oncogene family / P61026*	ENSDARG00000046106	40
rab3c / RAB3C, member RAS oncogene family	ENSDARG00000014462	39
rab3ab / RAB3A, member RAS oncogene family, b / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*	ENSDARG00000043835	39
rab13 / Q7T3A4 / RAB13, member RAS oncogene family / Q9DD03* / P51153* / Ras-related protein Rab-13 *	ENSDARG00000034771	39
rab3aa / RAB3A, member RAS oncogene family, a / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*	ENSDARG00000056347	38
rab8a / RAB8A, member RAS oncogene family / P55258* / P61006*	ENSDARG00000067920	38
megf8 / multiple EGF-like-domains 8	ENSDARG00000103934	37
rab3b / RAB3B, member RAS oncogene family / RAB3C* / Q9CZT8* / P20337* / P62823* / Q96E17* / RAB3C, member RAS oncogene family*	ENSDARG00000114797	37
rab8b / RAB8B, member RAS oncogene family / P61028* / Q92930*	ENSDARG00000068628	37
rab15 / RAB15, member RAS oncogene family / P59190*	ENSDARG00000026484	36
A5WW21 / zgc:162879	ENSDARG00000074163	31
rab27a / RAB27A, member RAS oncogene family / P51159*	ENSDARG00000103935	31
rab27b / RAB27B, member RAS oncogene family / O00194* / Q99P58*	ENSDARG00000087762	30
rab44 / RAB44, member RAS oncogene family / Q8CB87* / Ras-related protein Rab-44 *	ENSDARG00000028389	29
rasef / RAS and EF-hand domain containing / Q5RI75* / Q8IZ41* / Ras and EF-hand domain-containing protein homolog *	ENSDARG00000076250	29

Protein motifs (from Interpro)

Interpro ID	Name
IPR001806	Small GTPase superfamily
IPR005225	Small GTP-binding protein domain
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
cellular_component	GO:0005768	endosome	IBA
cellular_component	GO:0005794	Golgi apparatus	IBA
molecular_function	GO:0003924	GTPase activity	IEA
molecular_function	GO:0005525	GTP binding	IEA

Pathways (from Reactome)

Pathway description

RAB geranylgeranylation

RAB GEFs exchange GTP for GDP on RABs

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000056122	gdi1 / GDP dissociation inhibitor 1 / P31150* / P50396* / Rab GDP dissociation inhibitor alpha *	/ complex

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr