Manteia

ENSDARG00000034771

Danio rerio

Features

Gene ID:	ENSDARG00000034771

Biological name :	rab13

Synonyms :	Q7T3A4 / rab13 / RAB13, member RAS oncogene family

Possible biological names infered from orthology :	P51153 / Q9DD03 / Ras-related protein Rab-13

Species:	Danio rerio

Chr. number:	16
Strand:	1
Band:
Gene start:	23796612
Gene end:	23809611

Corresponding Affymetrix probe sets:	Dr.20822.1.S1_at (Zebrafish Array) NM_201329_at (Zebrafish Genome Array with custom cdf files)

Cross references:	Ensembl peptide - ENSDARP00000118739 Ensembl peptide - ENSDARP00000046921 NCBI entrez gene - 373105 See in Manteia. RefSeq - NM_201329 RefSeq Peptide - NP_958486 swissprot - E9QI28 swissprot - Q7T3A4 ZFIN ID - ZDB-GENE-030826-30 Ensembl - ENSDARG00000034771

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
RAB13	ENSG00000143545	Homo sapiens
Rab13	ENSMUSG00000027935	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
rab8a / RAB8A, member RAS oncogene family / P55258* / P61006*	ENSDARG00000067920	67
rab8b / RAB8B, member RAS oncogene family / P61028* / Q92930*	ENSDARG00000068628	67
megf8 / multiple EGF-like-domains 8	ENSDARG00000103934	63
rab10 / RAB10, member RAS oncogene family / P61026*	ENSDARG00000046106	63
rab15 / RAB15, member RAS oncogene family / P59190*	ENSDARG00000026484	51
rab3c / RAB3C, member RAS oncogene family	ENSDARG00000014462	48
rab3b / RAB3B, member RAS oncogene family / RAB3C* / Q9CZT8* / P20337* / P62823* / Q96E17* / RAB3C, member RAS oncogene family*	ENSDARG00000114797	47
rab3da / RAB3D, member RAS oncogene family, a / RAB3D* / P35276* / O95716* / RAB3D, member RAS oncogene family*	ENSDARG00000018107	47
rab12 / RAB12, member RAS oncogene family / Q6IQ22*	ENSDARG00000089428	46
rab3ab / RAB3A, member RAS oncogene family, b / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*	ENSDARG00000043835	46
rab3aa / RAB3A, member RAS oncogene family, a / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*	ENSDARG00000056347	45
rab3db / RAB3D, member RAS oncogene family, b / RAB3D* / P35276* / O95716* / RAB3D, member RAS oncogene family*	ENSDARG00000101534	45
rab44 / RAB44, member RAS oncogene family / Q8CB87* / Ras-related protein Rab-44 *	ENSDARG00000028389	41
rab27a / RAB27A, member RAS oncogene family / P51159*	ENSDARG00000103935	38
rab27b / RAB27B, member RAS oncogene family / O00194* / Q99P58*	ENSDARG00000087762	37
A5WW21 / zgc:162879	ENSDARG00000074163	34
rasef / RAS and EF-hand domain containing / Q5RI75* / Q8IZ41* / Ras and EF-hand domain-containing protein homolog *	ENSDARG00000076250	33

Protein motifs (from Interpro)

Interpro ID	Name
IPR001806	Small GTPase superfamily
IPR005225	Small GTP-binding protein domain
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001525	angiogenesis	IMP
biological_process	GO:0010737	protein kinase A signaling	ISS
biological_process	GO:0015031	protein transport	IEA
biological_process	GO:0030866	cortical actin cytoskeleton organization	ISS
biological_process	GO:0031175	neuron projection development	ISS
biological_process	GO:0032456	endocytic recycling	ISS
biological_process	GO:0032869	cellular response to insulin stimulus	ISS
biological_process	GO:0035767	endothelial cell chemotaxis	ISS
biological_process	GO:0044795	trans-Golgi network to recycling endosome transport	ISS
biological_process	GO:0070830	bicellular tight junction assembly	ISS
biological_process	GO:0072659	protein localization to plasma membrane	ISS
biological_process	GO:1902463	protein localization to cell leading edge	ISS
cellular_component	GO:0005768	endosome	IEA
cellular_component	GO:0005794	Golgi apparatus	IEA
cellular_component	GO:0005802	trans-Golgi network	ISS
cellular_component	GO:0005886	plasma membrane	ISS
cellular_component	GO:0005923	bicellular tight junction	ISS
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016328	lateral plasma membrane	ISS
cellular_component	GO:0030027	lamellipodium	ISS
cellular_component	GO:0030054	cell junction	IEA
cellular_component	GO:0030139	endocytic vesicle	ISS
cellular_component	GO:0030659	cytoplasmic vesicle membrane	IEA
cellular_component	GO:0031410	cytoplasmic vesicle	ISS
cellular_component	GO:0032593	insulin-responsive compartment	ISS
cellular_component	GO:0042995	cell projection	IEA
cellular_component	GO:0043005	neuron projection	ISS
cellular_component	GO:0055037	recycling endosome	ISS
cellular_component	GO:0055038	recycling endosome membrane	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0003924	GTPase activity	IEA
molecular_function	GO:0005525	GTP binding	IEA

Pathways (from Reactome)

Pathway description

RAB geranylgeranylation

RAB GEFs exchange GTP for GDP on RABs

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0001285	intersegmental vessel	intersegmental vessel arrested , abnormal intersegmental vessel decreased length , abnormal intersegmental vessel variability of size , abnormal intersegmental vessel endothelial tip cell shape , abnormal	Show
ZFA:0005025	dorsal longitudinal anastomotic vessel	dorsal longitudinal anastomotic vessel aplastic , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000056122	gdi1 / GDP dissociation inhibitor 1 / P31150* / P50396* / Rab GDP dissociation inhibitor alpha *	/ complex

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr