ENSG00000143545


Homo sapiens

Features
Gene ID: ENSG00000143545
  
Biological name :RAB13
  
Synonyms : P51153 / RAB13 / RAB13, member RAS oncogene family
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q21.3
Gene start: 153981617
Gene end: 153986358
  
Corresponding Affymetrix probe sets: 202252_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000480103
Ensembl peptide - ENSP00000357564
NCBI entrez gene - 5872     See in Manteia.
OMIM - 602672
RefSeq - XM_017001959
RefSeq - NM_001272038
RefSeq - NM_002870
RefSeq Peptide - NP_001258967
RefSeq Peptide - NP_002861
swissprot - P51153
swissprot - A0A087WWB9
Ensembl - ENSG00000143545
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab13ENSDARG00000034771Danio rerio
 Rab13ENSMUSG00000027935Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAB8B / Q92930 / RAB8B, member RAS oncogene familyENSG0000016612866
RAB8A / P61006 / RAB8A, member RAS oncogene familyENSG0000016746163
RAB10 / P61026 / RAB10, member RAS oncogene familyENSG0000008473361
RAB15 / P59190 / RAB15, member RAS oncogene familyENSG0000013999847
RAB3B / P20337 / RAB3B, member RAS oncogene familyENSG0000016921346
RAB12 / Q6IQ22 / RAB12, member RAS oncogene familyENSG0000020641846
RAB3C / Q96E17 / RAB3C, member RAS oncogene familyENSG0000015293245
RAB3A / P20336 / RAB3A, member RAS oncogene familyENSG0000010564945
RAB3D / O95716 / RAB3D, member RAS oncogene familyENSG0000010551444
O00194 / RAB27B / RAB27B, member RAS oncogene familyENSG0000004135339
P51159 / RAB27A / RAB27A, member RAS oncogene familyENSG0000006997439
RAB44 / RAB44, member RAS oncogene familyENSG0000025558735
RASEF / Q8IZ41 / RAS and EF-hand domain containingENSG0000016510534


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010737 protein kinase A signaling IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016197 endosomal transport IMP
 biological_processGO:0030866 cortical actin cytoskeleton organization IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0032456 endocytic recycling IEA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0035767 endothelial cell chemotaxis IEA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044795 trans-Golgi network to recycling endosome transport ISS
 biological_processGO:0070830 bicellular tight junction assembly IMP
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0097368 establishment of Sertoli cell barrier IEA
 biological_processGO:1902463 protein localization to cell leading edge IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016328 lateral plasma membrane IDA
 cellular_componentGO:0030027 lamellipodium ISS
 cellular_componentGO:0030054 cell junction TAS
 cellular_componentGO:0030139 endocytic vesicle IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0032593 insulin-responsive compartment IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IDA
 cellular_componentGO:0055037 recycling endosome IDA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0034236 protein kinase A catalytic subunit binding IEA


Pathways (from Reactome)
Pathway description
Translocation of SLC2A4 (GLUT4) to the plasma membrane
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000203879 GDI1 / P31150 / GDP dissociation inhibitor 1  / complex
 ENSG00000203668 CHML / P26374 / CHM like, Rab escort protein 2  / complex
 ENSG00000057608 GDI2 / P50395 / GDP dissociation inhibitor 2  / complex
 ENSG00000188419 CHM / P24386 / CHM, Rab escort protein 1  / complex






 

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