ENSG00000169213


Homo sapiens

Features
Gene ID: ENSG00000169213
  
Biological name :RAB3B
  
Synonyms : P20337 / RAB3B / RAB3B, member RAS oncogene family
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p32.3
Gene start: 51907956
Gene end: 51990764
  
Corresponding Affymetrix probe sets: 205924_at (Human Genome U133 Plus 2.0 Array)   205925_s_at (Human Genome U133 Plus 2.0 Array)   227123_at (Human Genome U133 Plus 2.0 Array)   239202_at (Human Genome U133 Plus 2.0 Array)   242629_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360718
NCBI entrez gene - 5865     See in Manteia.
OMIM - 179510
RefSeq - NM_002867
RefSeq - XM_017001958
RefSeq Peptide - NP_002858
swissprot - P20337
Ensembl - ENSG00000169213
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab3bENSDARG00000114797Danio rerio
 RAB3BENSGALG00000010567Gallus gallus
 Rab3bENSMUSG00000003411Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAB3C / Q96E17 / RAB3C, member RAS oncogene familyENSG0000015293281
RAB3A / P20336 / RAB3A, member RAS oncogene familyENSG0000010564978
RAB3D / O95716 / RAB3D, member RAS oncogene familyENSG0000010551476
RAB8A / P61006 / RAB8A, member RAS oncogene familyENSG0000016746147
RAB10 / P61026 / RAB10, member RAS oncogene familyENSG0000008473344
RAB12 / Q6IQ22 / RAB12, member RAS oncogene familyENSG0000020641843
RAB8B / Q92930 / RAB8B, member RAS oncogene familyENSG0000016612843
RAB13 / P51153 / RAB13, member RAS oncogene familyENSG0000014354542
P51159 / RAB27A / RAB27A, member RAS oncogene familyENSG0000006997440
RAB15 / P59190 / RAB15, member RAS oncogene familyENSG0000013999838
O00194 / RAB27B / RAB27B, member RAS oncogene familyENSG0000004135338
RAB44 / RAB44, member RAS oncogene familyENSG0000025558737
RASEF / Q8IZ41 / RAS and EF-hand domain containingENSG0000016510534


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0017157 regulation of exocytosis IEA
 biological_processGO:0018125 peptidyl-cysteine methylation IEA
 biological_processGO:0019882 antigen processing and presentation IMP
 biological_processGO:0051586 positive regulation of dopamine uptake involved in synaptic transmission IDA
 biological_processGO:0097494 regulation of vesicle size IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030141 secretory granule IEA
 cellular_componentGO:0031982 vesicle IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0098993 anchored component of synaptic vesicle membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019003 GDP binding IDA
 molecular_functionGO:0030742 GTP-dependent protein binding IEA
 molecular_functionGO:0031489 myosin V binding IPI


Pathways (from Reactome)
Pathway description
RAB geranylgeranylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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