ENSG00000105514


Homo sapiens

Features
Gene ID: ENSG00000105514
  
Biological name :RAB3D
  
Synonyms : O95716 / RAB3D / RAB3D, member RAS oncogene family
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.2
Gene start: 11322046
Gene end: 11346270
  
Corresponding Affymetrix probe sets: 208466_at (Human Genome U133 Plus 2.0 Array)   225001_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000222120
Ensembl peptide - ENSP00000466000
NCBI entrez gene - 9545     See in Manteia.
OMIM - 604350
RefSeq - NM_004283
RefSeq Peptide - NP_004274
swissprot - A0A024R7G2
swissprot - O95716
Ensembl - ENSG00000105514
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab3daENSDARG00000018107Danio rerio
 rab3dbENSDARG00000101534Danio rerio
 Rab3dENSMUSG00000019066Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAB3A / P20336 / RAB3A, member RAS oncogene familyENSG0000010564977
RAB3B / P20337 / RAB3B, member RAS oncogene familyENSG0000016921376
RAB3C / Q96E17 / RAB3C, member RAS oncogene familyENSG0000015293274
RAB8A / P61006 / RAB8A, member RAS oncogene familyENSG0000016746146
RAB10 / P61026 / RAB10, member RAS oncogene familyENSG0000008473344
RAB8B / Q92930 / RAB8B, member RAS oncogene familyENSG0000016612843
RAB12 / Q6IQ22 / RAB12, member RAS oncogene familyENSG0000020641841
RAB13 / P51153 / RAB13, member RAS oncogene familyENSG0000014354541
O00194 / RAB27B / RAB27B, member RAS oncogene familyENSG0000004135341
P51159 / RAB27A / RAB27A, member RAS oncogene familyENSG0000006997440
RAB15 / P59190 / RAB15, member RAS oncogene familyENSG0000013999838
RAB44 / RAB44, member RAS oncogene familyENSG0000025558737
RASEF / Q8IZ41 / RAS and EF-hand domain containingENSG0000016510531


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0017157 regulation of exocytosis IEA
 biological_processGO:0018125 peptidyl-cysteine methylation IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045453 bone resorption IDA
 biological_processGO:1903307 positive regulation of regulated secretory pathway IMP
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005881 cytoplasmic microtubule IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030133 transport vesicle IEA
 cellular_componentGO:0035577 azurophil granule membrane TAS
 cellular_componentGO:0042588 zymogen granule IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0099503 secretory vesicle IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity TAS
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0030742 GTP-dependent protein binding IEA
 molecular_functionGO:0031489 myosin V binding IPI


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
RAB geranylgeranylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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