ENSMUSG00000027935


Mus musculus

Features
Gene ID: ENSMUSG00000027935
  
Biological name :Rab13
  
Synonyms : Q9DD03 / Rab13 / Ras-related protein Rab-13
  
Possible biological names infered from orthology : P51153 / RAB13, member RAS oncogene family
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F1
Gene start: 90213695
Gene end: 90226385
  
Corresponding Affymetrix probe sets: 10493692 (MoGene1.0st)   1424894_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000070588
Ensembl peptide - ENSMUSP00000102996
NCBI entrez gene - 68328     See in Manteia.
MGI - MGI:1927232
RefSeq - NM_001293741
RefSeq - NM_026677
RefSeq Peptide - NP_001280670
RefSeq Peptide - NP_080953
swissprot - Q9DD03
swissprot - D3YUS4
Ensembl - ENSMUSG00000027935
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab13ENSDARG00000034771Danio rerio
 RAB13ENSG00000143545Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rab8b / P61028 / RAB8B, member RAS oncogene family / Q92930*ENSMUSG0000003694365
Rab8a / P55258 / RAB8A, member RAS oncogene family / P61006*ENSMUSG0000000303765
Rab10 / P61027 / RAB10, member RAS oncogene family / P61026*ENSMUSG0000002067161
Rab12 / P35283 / Ras-related protein Rab-12 / Q6IQ22* / RAB12, member RAS oncogene family*ENSMUSG0000002346047
Rab15 / RAB15, member RAS oncogene family / P59190*ENSMUSG0000002106247
Rab3a / P63011 / RAB3A, member RAS oncogene family / P20336*ENSMUSG0000003184046
Rab3c / P62823 / RAB3C, member RAS oncogene family / Q96E17*ENSMUSG0000002170046
Rab3b / Q9CZT8 / RAB3B, member RAS oncogene family / P20337*ENSMUSG0000000341146
Rab3d / P35276 / RAB3D, member RAS oncogene family / O95716*ENSMUSG0000001906645
Q9ERI2 / Rab27a / RAB27A, member RAS oncogene family / P51159*ENSMUSG0000003220240
Q99P58 / Rab27b / RAB27B, member RAS oncogene family / O00194*ENSMUSG0000002451139
Rab44 / Q8CB87 / Ras-related protein Rab-44 / RAB44, member RAS oncogene family*ENSMUSG0000006414733
Rasef / Q5RI75 / Ras and EF-hand domain-containing protein homolog / Q8IZ41* / RAS and EF-hand domain containing*ENSMUSG0000004300333


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport TAS
 biological_processGO:0010737 protein kinase A signaling IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016197 endosomal transport IEA
 biological_processGO:0030866 cortical actin cytoskeleton organization IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0032456 endocytic recycling IEA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0035767 endothelial cell chemotaxis IMP
 biological_processGO:0044795 trans-Golgi network to recycling endosome transport ISS
 biological_processGO:0070830 bicellular tight junction assembly IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0097368 establishment of Sertoli cell barrier IEA
 biological_processGO:1902463 protein localization to cell leading edge IMP
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016328 lateral plasma membrane IEA
 cellular_componentGO:0019897 extrinsic component of plasma membrane TAS
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030139 endocytic vesicle IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane TAS
 cellular_componentGO:0031410 cytoplasmic vesicle TAS
 cellular_componentGO:0032593 insulin-responsive compartment IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0055037 recycling endosome IEA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity TAS
 molecular_functionGO:0005525 GTP binding ISO
 molecular_functionGO:0034236 protein kinase A catalytic subunit binding IEA


Pathways (from Reactome)
Pathway description
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000015291 Gdi1 / P50396 / Rab GDP dissociation inhibitor alpha / P31150* / GDP dissociation inhibitor 1*  / complex
 ENSMUSG00000025531 Chm / choroidermia (RAB escort protein 1) / P24386* / CHM, Rab escort protein 1*  / complex
 ENSMUSG00000021218 Gdi2 / Q61598 / Rab GDP dissociation inhibitor beta / P50395* / GDP dissociation inhibitor 2*  / complex
 ENSMUSG00000078185 Chml / choroideremia-like / P26374* / CHM like, Rab escort protein 2*  / complex






 

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