ENSMUSG00000021062


Mus musculus

Features
Gene ID: ENSMUSG00000021062
  
Biological name :Rab15
  
Synonyms : Rab15 / RAB15, member RAS oncogene family
  
Possible biological names infered from orthology : P59190
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: C3
Gene start: 76797960
Gene end: 76822908
  
Corresponding Affymetrix probe sets: 10401114 (MoGene1.0st)   1417829_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112457
Ensembl peptide - ENSMUSP00000122067
Ensembl peptide - ENSMUSP00000115720
Ensembl peptide - ENSMUSP00000113299
Ensembl peptide - ENSMUSP00000112789
Ensembl peptide - ENSMUSP00000021459
NCBI entrez gene - 104886     See in Manteia.
MGI - MGI:1916865
RefSeq - NM_134050
RefSeq - XM_006515369
RefSeq - XM_006515368
RefSeq - XM_006515367
RefSeq Peptide - NP_001334335
RefSeq Peptide - NP_001334334
RefSeq Peptide - NP_001334336
RefSeq Peptide - NP_598811
swissprot - D3YYX5
swissprot - Q3TYH2
swissprot - D3YTZ8
swissprot - D3Z1A7
swissprot - D3YWS1
Ensembl - ENSMUSG00000021062
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab15ENSDARG00000026484Danio rerio
 RAB15ENSG00000139998Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rab10 / P61027 / RAB10, member RAS oncogene family / P61026*ENSMUSG0000002067146
Rab8a / P55258 / RAB8A, member RAS oncogene family / P61006*ENSMUSG0000000303746
Rab8b / P61028 / RAB8B, member RAS oncogene family / Q92930*ENSMUSG0000003694346
Rab13 / Q9DD03 / Ras-related protein Rab-13 / P51153* / RAB13, member RAS oncogene family*ENSMUSG0000002793545
Rab12 / P35283 / Ras-related protein Rab-12 / Q6IQ22* / RAB12, member RAS oncogene family*ENSMUSG0000002346042
Rab3c / P62823 / RAB3C, member RAS oncogene family / Q96E17*ENSMUSG0000002170040
Rab3d / P35276 / RAB3D, member RAS oncogene family / O95716*ENSMUSG0000001906639
Rab3a / P63011 / RAB3A, member RAS oncogene family / P20336*ENSMUSG0000003184039
Rab3b / Q9CZT8 / RAB3B, member RAS oncogene family / P20337*ENSMUSG0000000341138
Q99P58 / Rab27b / RAB27B, member RAS oncogene family / O00194*ENSMUSG0000002451135
Rab44 / Q8CB87 / Ras-related protein Rab-44 / RAB44, member RAS oncogene family*ENSMUSG0000006414734
Rasef / Q5RI75 / Ras and EF-hand domain-containing protein homolog / Q8IZ41* / RAS and EF-hand domain containing*ENSMUSG0000004300333
Q9ERI2 / Rab27a / RAB27A, member RAS oncogene family / P51159*ENSMUSG0000003220233


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:1903307 positive regulation of regulated secretory pathway IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
RAB geranylgeranylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Psen1tm1.1(KOMP)Vlcg/Psen1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psen1tm1.1(KOMP)Vlcg/J

 MP:0001513 limb grasping "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Psen1tm1.1(KOMP)Vlcg/Psen1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psen1tm1.1(KOMP)Vlcg/J

 MP:0003345 decreased number of ribs "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Psen1tm1.1(KOMP)Vlcg/Psen1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psen1tm1.1(KOMP)Vlcg/J

 MP:0004647 decreased lumbar vertebrae number "reduced number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
Show

Allelic Composition: Psen1tm1.1(KOMP)Vlcg/Psen1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psen1tm1.1(KOMP)Vlcg/J

 MP:0005103 abnormal retinal pigmentation "anomalous coloring of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Psen1tm1.1(KOMP)Vlcg/Psen1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psen1tm1.1(KOMP)Vlcg/J

 MP:0010101 increased sacral vertebrae number "increase of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Psen1tm1.1(KOMP)Vlcg/Psen1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psen1tm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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