ENSDARG00000046106


Danio rerio

Features
Gene ID: ENSDARG00000046106
  
Biological name :rab10
  
Synonyms : rab10 / RAB10, member RAS oncogene family
  
Possible biological names infered from orthology : P61026 / P61027
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 47434709
Gene end: 47471595
  
Corresponding Affymetrix probe sets: Dr.10561.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000067775
NCBI entrez gene - 436839     See in Manteia.
RefSeq - NM_001002566
RefSeq Peptide - NP_001002566
swissprot - Q6DGV5
ZFIN ID - ZDB-GENE-040718-304
Ensembl - ENSDARG00000046106
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAB10ENSGALG00000016535Gallus gallus
 RAB10ENSG00000084733Homo sapiens
 Rab10ENSMUSG00000020671Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rab8a / RAB8A, member RAS oncogene family / P55258* / P61006*ENSDARG0000006792070
rab8b / RAB8B, member RAS oncogene family / P61028* / Q92930*ENSDARG0000006862868
megf8 / multiple EGF-like-domains 8ENSDARG0000010393465
rab13 / Q7T3A4 / RAB13, member RAS oncogene family / Q9DD03* / P51153* / Ras-related protein Rab-13 *ENSDARG0000003477163
rab15 / RAB15, member RAS oncogene family / P59190*ENSDARG0000002648449
rab3da / RAB3D, member RAS oncogene family, a / RAB3D* / P35276* / O95716* / RAB3D, member RAS oncogene family*ENSDARG0000001810747
rab12 / RAB12, member RAS oncogene family / Q6IQ22*ENSDARG0000008942847
rab3c / RAB3C, member RAS oncogene familyENSDARG0000001446247
rab3db / RAB3D, member RAS oncogene family, b / RAB3D* / P35276* / O95716* / RAB3D, member RAS oncogene family*ENSDARG0000010153446
rab3b / RAB3B, member RAS oncogene family / RAB3C* / Q9CZT8* / P20337* / P62823* / Q96E17* / RAB3C, member RAS oncogene family*ENSDARG0000011479746
rab3aa / RAB3A, member RAS oncogene family, a / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*ENSDARG0000005634746
rab3ab / RAB3A, member RAS oncogene family, b / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*ENSDARG0000004383546
rab27a / RAB27A, member RAS oncogene family / P51159*ENSDARG0000010393539
rab27b / RAB27B, member RAS oncogene family / O00194* / Q99P58*ENSDARG0000008776239
rab44 / RAB44, member RAS oncogene family / Q8CB87* / Ras-related protein Rab-44 *ENSDARG0000002838938
A5WW21 / zgc:162879ENSDARG0000007416335
rasef / RAS and EF-hand domain containing / Q5RI75* / Q8IZ41* / Ras and EF-hand domain-containing protein homolog *ENSDARG0000007625034


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006904 vesicle docking involved in exocytosis IBA
 biological_processGO:0009306 protein secretion IBA
 biological_processGO:0017157 regulation of exocytosis IBA
 biological_processGO:0032869 cellular response to insulin stimulus IBA
 biological_processGO:0061564 axon development IMP
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0032593 insulin-responsive compartment IBA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000435 cranial nerve II cranial nerve II decreased width , abnormal
cranial nerve II has fewer parts of type retinal ganglion cell axon, abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000056122 gdi1 / GDP dissociation inhibitor 1 / P31150* / P50396* / Rab GDP dissociation inhibitor alpha *  / complex
 ENSDARG00000062721 dennd4a / DENN/MADD domain containing 4A / Q7Z401* / DENN domain containing 4A*  / reaction
 ENSDARG00000102914 dennd4b / DENN/MADD domain containing 4B / O75064* / Q3U1Y4* / DENN domain containing 4B* / Mus musculus DENN/MADD domain containing 4B (Dennd4b), transcript variant 2, mRNA.*  / reaction
 ENSDARG00000102766 dennd4c / DENN/MADD domain containing 4C / Q5VZ89* / DENN domain containing 4C*  / reaction






 

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