ENSGALG00000003487


Gallus gallus

Features
Gene ID: ENSGALG00000003487
  
Biological name :RAB8B
  
Synonyms : RAB8B / RAB8B, member RAS oncogene family
  
Possible biological names infered from orthology : P61028 / Q92930
  
Species: Gallus gallus
  
Chr. number: 10
Strand: -1
Band:
Gene start: 4056133
Gene end: 4078464
  
Corresponding Affymetrix probe sets: Gga.11709.1.S1_at (Chicken Array)   Gga.13026.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005505
NCBI entrez gene - 415371     See in Manteia.
RefSeq - XM_004943742
RefSeq - XM_015278958
RefSeq - XM_015278956
RefSeq - XM_015278957
swissprot - E1C080
Ensembl - ENSGALG00000003487
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab8bENSDARG00000068628Danio rerio
 RAB8BENSG00000166128Homo sapiens
 Rab8bENSMUSG00000036943Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAB8A / Q5F470 / Ras-related protein Rab-8A / P61006* / P55258* / RAB8A, member RAS oncogene family*ENSGALG0000002885181
RAB10 / ras-related protein Rab-10 / P61026* / P61027* / RAB10, member RAS oncogene family*ENSGALG0000001653569
RAB3A / RAB3A, member RAS oncogene family / P20336* / P63011*ENSGALG0000003006846
RAB3C / RAB3C, member RAS oncogene family / P62823* / Q96E17*ENSGALG0000001472645
RAB12 / RAB12, member RAS oncogene family / P35283* / Q6IQ22* / Ras-related protein Rab-12 *ENSGALG0000003360843
RAB27A / RAB27A, member RAS oncogene family / P51159* / Q9ERI2*ENSGALG0000000443542
ENSGALG0000001518338
RAB3B / RAB3B, member RAS oncogene family / P20337* / Q9CZT8*ENSGALG0000001056738
RASEF / RAS and EF-hand domain containing / Q5RI75* / Q8IZ41* / Ras and EF-hand domain-containing protein homolog *ENSGALG0000001257634
ENSGALG0000004648833
RAB44 / RAB44, member RAS oncogene family / Q8CB87* / Ras-related protein Rab-44 *ENSGALG0000000054432


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006904 vesicle docking involved in exocytosis IBA
 biological_processGO:0009306 protein secretion IBA
 biological_processGO:0017157 regulation of exocytosis IBA
 biological_processGO:0019882 antigen processing and presentation IEA
 biological_processGO:0045046 protein import into peroxisome membrane IEA
 biological_processGO:0072659 protein localization to plasma membrane IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005768 endosome IBA
 cellular_componentGO:0005778 peroxisomal membrane IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0008021 synaptic vesicle IBA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0030667 secretory granule membrane IBA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0045335 phagocytic vesicle IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019003 GDP binding IEA


Pathways (from Reactome)
Pathway description
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000013738 OPTN / Q90Z16 / Optineurin / Q8K3K8* / Q96CV9* / Mus musculus optineurin (Optn), transcript variant 1, mRNA.*  / complex






 

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