ENSGALG00000005554


Gallus gallus

Features
Gene ID: ENSGALG00000005554
  
Biological name :ADIPOQ
  
Synonyms : adiponectin precursor / ADIPOQ
  
Possible biological names infered from orthology : Adiponectin / adiponectin, C1Q and collagen domain containing / Q15848 / Q60994
  
Species: Gallus gallus
  
Chr. number: 9
Strand: -1
Band:
Gene start: 5223114
Gene end: 5225251
  
Corresponding Affymetrix probe sets: Gga.16038.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000008899
NCBI entrez gene - 404536     See in Manteia.
RefSeq - NM_206991
RefSeq - XM_015276846
RefSeq Peptide - NP_996874
swissprot - F1NRD4
Ensembl - ENSGALG00000005554
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adipoqaENSDARG00000062228Danio rerio
 adipoqbENSDARG00000100086Danio rerio
 ADIPOQENSG00000181092Homo sapiens
 AdipoqENSMUSG00000022878Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OTOL1 / otolin 1 / A6NHN0* / Q4ZJM7*ENSGALG0000002630542
B2RNN3* / P0C862* / Q4ZJN1* / C1QTNF9* / C1QTNF9B* / C1q and TNF related 9* / C1q and TNF related 9B* / Complement C1q and tumor necrosis factor-related protein 9 *ENSGALG0000001711742
C1QTNF2 / C1q and TNF related 2 / Q9BXJ5* / Q9D8U4* / Complement C1q tumor necrosis factor-related protein 2 *ENSGALG0000002723240
COL10A1 / collagen type X alpha 1 chain / Q03692* / Q05306* / Collagen alpha-1(X) chain *ENSGALG0000001496539
C1QC / complement C1q C chain / P02747* / Q02105* / Complement C1q subcomponent subunit C *ENSGALG0000002966939
C1QTNF7 / C1q and TNF related 7 / Q8BVD7* / Q9BXJ2* / Complement C1q tumor necrosis factor-related protein 7 *ENSGALG0000001451538
COL8A1 / collagen alpha-1(VIII) chain precursor / P27658* / Q00780* / collagen type VIII alpha 1 chain* / Collagen alpha-1(VIII) chain Vastatin*ENSGALG0000001525336
COL8A2 / collagen type VIII alpha 2 chain / P25067* / P25318* / Collagen alpha-2(VIII) chain *ENSGALG0000000229836
C1QTNF5 / C1q and TNF related 5 / Q8K479* / Q9BXJ0* / Complement C1q tumor necrosis factor-related protein 5 *ENSGALG0000000675835
C1QB / complement C1q B chain / P02746* / P14106* / Complement C1q subcomponent subunit B *ENSGALG0000000477132


Protein motifs (from Interpro)
Interpro ID Name
 IPR001073  C1q domain
 IPR008160  Collagen triple helix repeat
 IPR008983  Tumour necrosis factor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0006006 glucose metabolic process IEA
 biological_processGO:0006635 fatty acid beta-oxidation IEA
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway IEA
 biological_processGO:0010739 positive regulation of protein kinase A signaling IEA
 biological_processGO:0010745 negative regulation of macrophage derived foam cell differentiation IEA
 biological_processGO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway IEA
 biological_processGO:0010875 positive regulation of cholesterol efflux IEA
 biological_processGO:0010906 regulation of glucose metabolic process IEA
 biological_processGO:0019395 fatty acid oxidation IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0030853 negative regulation of granulocyte differentiation IEA
 biological_processGO:0031953 negative regulation of protein autophosphorylation IEA
 biological_processGO:0032270 positive regulation of cellular protein metabolic process IEA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IEA
 biological_processGO:0032757 positive regulation of interleukin-8 production IEA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0033034 positive regulation of myeloid cell apoptotic process IEA
 biological_processGO:0034115 negative regulation of heterotypic cell-cell adhesion IEA
 biological_processGO:0034383 low-density lipoprotein particle clearance IEA
 biological_processGO:0034612 response to tumor necrosis factor IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043407 negative regulation of MAP kinase activity IEA
 biological_processGO:0045599 negative regulation of fat cell differentiation IEA
 biological_processGO:0045650 negative regulation of macrophage differentiation IEA
 biological_processGO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process IEA
 biological_processGO:0045721 negative regulation of gluconeogenesis IEA
 biological_processGO:0045776 negative regulation of blood pressure IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045923 positive regulation of fatty acid metabolic process IEA
 biological_processGO:0046326 positive regulation of glucose import IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0050765 negative regulation of phagocytosis IEA
 biological_processGO:0050805 negative regulation of synaptic transmission IEA
 biological_processGO:0050873 brown fat cell differentiation IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0070208 protein heterotrimerization IEA
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0070994 detection of oxidative stress IEA
 biological_processGO:0071639 positive regulation of monocyte chemotactic protein-1 production IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0090317 negative regulation of intracellular protein transport IEA
 biological_processGO:1900121 negative regulation of receptor binding IEA
 biological_processGO:1904706 negative regulation of vascular smooth muscle cell proliferation IEA
 biological_processGO:1904753 negative regulation of vascular associated smooth muscle cell migration IEA
 biological_processGO:2000279 negative regulation of DNA biosynthetic process IEA
 biological_processGO:2000478 positive regulation of metanephric glomerular visceral epithelial cell development IEA
 biological_processGO:2000481 positive regulation of cAMP-dependent protein kinase activity IEA
 biological_processGO:2000534 positive regulation of renal albumin absorption IEA
 biological_processGO:2000584 negative regulation of platelet-derived growth factor receptor-alpha signaling pathway IEA
 biological_processGO:2000590 negative regulation of metanephric mesenchymal cell migration IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005581 collagen trimer IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0009986 cell surface IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0033691 sialic acid binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
AMPK inhibits chREBP transcriptional activation activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000005554 ADIPOQ / adiponectin precursor / Q15848* / Q60994* / Adiponectin * / adiponectin, C1Q and collagen domain containing*  / complex
 ENSGALG00000035533 ADIPOR2 / adiponectin receptor 2 / Q86V24* / Q8BQS5*  / reaction / complex
 ENSGALG00000000094 ADIPOR1 / adiponectin receptor protein 1 / Q91VH1* / Q96A54* / adiponectin receptor 1*  / reaction / complex






 

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