ENSGALG00000006560


Gallus gallus

Features
Gene ID: ENSGALG00000006560
  
Biological name :SEMA3A
  
Synonyms : SEMA3A / semaphorin-3A
  
Possible biological names infered from orthology : O08665 / Q14563
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 8824964
Gene end: 8995709
  
Corresponding Affymetrix probe sets: Gga.487.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010577
Ensembl peptide - ENSGALP00000042260
NCBI entrez gene - 395825     See in Manteia.
RefSeq - XM_015295177
RefSeq - NM_204977
RefSeq Peptide - NP_990308
swissprot - R4GJE6
swissprot - F1NVZ5
Ensembl - ENSGALG00000006560
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sema3aaENSDARG00000019235Danio rerio
 sema3abENSDARG00000042210Danio rerio
 Q14563ENSG00000075213Homo sapiens
 O08665ENSMUSG00000028883Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q90663 / SEMA3D / Semaphorin-3D / O95025* / Q8BH34*ENSGALG0000000656351
SEMA3B / semaphorin 3B / Q13214* / sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B*ENSGALG0000001372247
SEMA3E / semaphorin-3E precursor / P70275* / O15041* / semaphorin 3E* / sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E*ENSGALG0000003822543
SEMA3C / semaphorin-3C precursor / Q62181* / Q99985* / semaphorin 3C*ENSGALG0000004044443
SEMA3G / semaphorin 3G / Q4LFA9* / Q9NS98*ENSGALG0000000447643
SEMA3F / semaphorin-3F precursor / O88632* / Q13275* / semaphorin 3F*ENSGALG0000002962142
SEMA4D / semaphorin-4D precursor / O09126* / Q92854* / semaphorin 4D*ENSGALG0000001069731
SEMA4G / semaphorin 4G / Q9NTN9* / Q9WUH7*ENSGALG0000002695729
SEMA4B / semaphorin 4B / Q62179*ENSGALG0000000829727
ENSGALG0000000305827


Protein motifs (from Interpro)
Interpro ID Name
 IPR001627  Sema domain
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016201  PSI domain
 IPR027231  Semaphorin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0002027 regulation of heart rate IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0007413 axonal fasciculation IEA
 biological_processGO:0008045 motor neuron axon guidance IMP
 biological_processGO:0010633 negative regulation of epithelial cell migration IEA
 biological_processGO:0010977 negative regulation of neuron projection development IEA
 biological_processGO:0021612 facial nerve structural organization IEA
 biological_processGO:0021637 trigeminal nerve structural organization IEA
 biological_processGO:0021675 nerve development IEA
 biological_processGO:0021772 olfactory bulb development IEA
 biological_processGO:0021785 branchiomotor neuron axon guidance IEA
 biological_processGO:0021828 gonadotrophin-releasing hormone neuronal migration to the hypothalamus IEA
 biological_processGO:0030517 negative regulation of axon extension IEA
 biological_processGO:0036486 ventral trunk neural crest cell migration IEA
 biological_processGO:0048813 dendrite morphogenesis IEA
 biological_processGO:0048841 regulation of axon extension involved in axon guidance IEA
 biological_processGO:0048843 negative regulation of axon extension involved in axon guidance IEA
 biological_processGO:0048846 axon extension involved in axon guidance IEA
 biological_processGO:0050919 negative chemotaxis IEA
 biological_processGO:0060385 axonogenesis involved in innervation IEA
 biological_processGO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching IEA
 biological_processGO:0061549 sympathetic ganglion development IEA
 biological_processGO:0061551 trigeminal ganglion development IEA
 biological_processGO:0071526 semaphorin-plexin signaling pathway IEA
 biological_processGO:0097156 fasciculation of motor neuron axon IMP
 biological_processGO:0097490 sympathetic neuron projection extension IEA
 biological_processGO:0097491 sympathetic neuron projection guidance IEA
 biological_processGO:0150020 basal dendrite arborization IEA
 biological_processGO:1901166 neural crest cell migration involved in autonomic nervous system development IEA
 biological_processGO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance IEA
 biological_processGO:1902287 semaphorin-plexin signaling pathway involved in axon guidance IEA
 biological_processGO:1903045 neural crest cell migration involved in sympathetic nervous system development IEA
 biological_processGO:1903375 facioacoustic ganglion development IEA
 biological_processGO:1990535 neuron projection maintenance IMP
 biological_processGO:2000009 negative regulation of protein localization to cell surface IMP
 biological_processGO:2000020 positive regulation of male gonad development IEA
 biological_processGO:2001224 positive regulation of neuron migration IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0044297 cell body IDA
 molecular_functionGO:0030215 semaphorin receptor binding IEA
 molecular_functionGO:0038191 neuropilin binding IPI
 molecular_functionGO:0045499 chemorepellent activity IEA


Pathways (from Reactome)
Pathway description
Sema3A PAK dependent Axon repulsion
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
CRMPs in Sema3A signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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