ENSGALG00000007247


Gallus gallus

Features
Gene ID: ENSGALG00000007247
  
Biological name :PXN
  
Synonyms : paxillin / PXN
  
Possible biological names infered from orthology : P49023 / Q8VI36
  
Species: Gallus gallus
  
Chr. number: 15
Strand: 1
Band:
Gene start: 9439877
Gene end: 9480089
  
Corresponding Affymetrix probe sets: Gga.4056.1.S1_at (Chicken Array)   Gga.4056.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051886
Ensembl peptide - ENSGALP00000011713
NCBI entrez gene - 395832     See in Manteia.
RefSeq - XM_015275216
RefSeq - XM_015275209
RefSeq - XM_015275210
RefSeq - XM_015275211
RefSeq - NM_204984
RefSeq - XM_015275206
RefSeq - XM_015275207
RefSeq - XM_015275208
RefSeq Peptide - NP_990315
swissprot - F1NB68
swissprot - A0A1D5PGG4
Ensembl - ENSGALG00000007247
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pxnaENSDARG00000088590Danio rerio
 pxnbENSDARG00000060766Danio rerio
 PXNENSG00000089159Homo sapiens
 PxnENSMUSG00000029528Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDLIM5 / PDZ and LIM domain protein 5 / Q8CI51* / Q96HC4* / PDZ and LIM domain 5*ENSGALG0000001221118
PDLIM7 / PDZ and LIM domain protein 7 / Q3TJD7* / Q9NR12* / PDZ and LIM domain 7*ENSGALG0000002615917
LIMS2* / Q7Z4I7* / Q91XD2* / LIM zinc finger domain containing 2* / LIM and senescent cell antigen-like-containing domain protein 2 *ENSGALG0000000199513
FHL3 / four and a half LIM domains 3 / Q13643* / Q9R059* / Four and a half LIM domains protein 3 *ENSGALG0000003518712
FHL2 / four and a half LIM domains 2 / O70433* / Q14192* / Four and a half LIM domains protein 2 *ENSGALG0000001679712
LIMS1 / LIM and senescent cell antigen-like-containing domain protein 1 / AC013271.1* / AC112229.3* / Mus musculus LIM and senescent cell antigen-like domains 1 (Lims1), transcript variant 6, mRNA.*ENSGALG0000002997012
FHL1 / four and a half LIM domains 1 / Fhl4* / P97447* / Q13642* / Four and a half LIM domains protein 1 *ENSGALG0000000619011
FHL5 / four and a half LIM domains 5 / Q5TD97* / Q9WTX7* / Four and a half LIM domains protein 5 *ENSGALG0000001557311
ENSGALG000000458157
ENSGALG000000442587
LIMS2* / Q7Z4I7* / Q91XD2* / LIM zinc finger domain containing 2* / LIM and senescent cell antigen-like-containing domain protein 2 *ENSGALG000000439665
LIMS2* / Q7Z4I7* / Q91XD2* / LIM zinc finger domain containing 2* / LIM and senescent cell antigen-like-containing domain protein 2 *ENSGALG000000450555
LDB3ENSGALG000000019774


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type
 IPR001904  Paxillin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0034614 cellular response to reactive oxygen species IEA
 biological_processGO:0035994 response to muscle stretch IDA
 biological_processGO:0043542 endothelial cell migration IEA
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 biological_processGO:0060396 growth hormone receptor signaling pathway IEA
 cellular_componentGO:0001725 stress fiber IEA
 cellular_componentGO:0005623 cell IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0030027 lamellipodium IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0017166 vinculin binding IEA
 molecular_functionGO:0038191 neuropilin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
GAB1 signalosome
VEGFA-VEGFR2 Pathway
Smooth Muscle Contraction
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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