ENSGALG00000007435


Gallus gallus

Features
Gene ID: ENSGALG00000007435
  
Biological name :RAB18
  
Synonyms : Q5ZLG1 / RAB18 / Ras-related protein Rab-18
  
Possible biological names infered from orthology : P35293 / Q9NP72 / RAB18, member RAS oncogene family
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 15789001
Gene end: 15802561
  
Corresponding Affymetrix probe sets: GgaAffx.11876.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012019
Ensembl peptide - ENSGALP00000062764
NCBI entrez gene - 420483     See in Manteia.
RefSeq - NM_001006355
RefSeq Peptide - NP_001006355
swissprot - Q5ZLG1
Ensembl - ENSGALG00000007435
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6DHC1ENSDARG00000098344Danio rerio
 rab18aENSDARG00000055291Danio rerio
 RAB18ENSG00000099246Homo sapiens
 Rab18ENSMUSG00000073639Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000004043445
RAB2A / Q90965 / Ras-related protein Rab-2A / P61019* / P53994* / RAB2A, member RAS oncogene family*ENSGALG0000001545044
RAB11B / ras-related protein Rab-11B ENSGALG0000000061341
Q5ZJN2 / RAB11A / Ras-related protein Rab-11A / P62491* / P62492* / RAB11A, member RAS oncogene family*ENSGALG0000000761541
RAB14 / Q5ZKU5 / Ras-related protein Rab-14 / Q91V41* / P61106* / RAB14, member RAS oncogene family*ENSGALG0000000147440
RAB25* / P57735* / Q9WTL2* / RAB25, member RAS oncogene family*ENSGALG0000002981238
RAB4A / RAB4A, member RAS oncogene family / P20338* / P56371* / Ras-related protein Rab-4A *ENSGALG0000003621838
RAB39A / RAB39A, member RAS oncogene family / Rab39* / Q8BHD0* / Q14964* / RAB39, member RAS oncogene family*ENSGALG0000001716636
RAB11B / RAB11B, member RAS oncogene family / P46638* / Q15907*ENSGALG0000003780236
RAB39B / RAB39B, member RAS oncogene family / Q8BHC1* / Q96DA2*ENSGALG0000004078435
RAB42* / Q0PD08* / Q8N4Z0* / Ras-related protein Rab-42 * / RAB42, member RAS oncogene family*ENSGALG0000000099433


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR025662  Sigma-54 interaction domain, ATP-binding site 1
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007420 brain development ISS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0034389 lipid particle organization IBA
 biological_processGO:0051170 import into nucleus IEA
 biological_processGO:0071786 endoplasmic reticulum tubular network organization IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0071782 endoplasmic reticulum tubular network IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019003 GDP binding ISS


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
COPI-independent Golgi-to-ER retrograde traffic
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000012214 RAB3GAP1 / RAB3 GTPase activating protein catalytic subunit 1 / Q15042* / Q80UJ7* / Rab3 GTPase-activating protein catalytic subunit *  / complex / reaction
 ENSGALG00000009503 RAB3GAP2 / RAB3 GTPase activating non-catalytic protein subunit 2 / Q9H2M9*  / reaction / complex






 

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