ENSGALG00000008218


Gallus gallus

Features
Gene ID: ENSGALG00000008218
  
Biological name :DDB2
  
Synonyms : DDB2 / DNA damage-binding protein 2 / Q5ZJL7
  
Possible biological names infered from orthology : damage specific DNA binding protein 2 / Q92466 / Q99J79
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 23152839
Gene end: 23167347
  
Corresponding Affymetrix probe sets: GgaAffx.12520.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013362
NCBI entrez gene - 423185     See in Manteia.
RefSeq - XM_015287025
RefSeq - NM_001039301
RefSeq - XM_015287023
RefSeq - XM_015287024
RefSeq - XM_015287017
RefSeq - XM_015287018
RefSeq - XM_015287019
RefSeq - XM_015287020
RefSeq - XM_015287021
RefSeq - XM_015287022
RefSeq Peptide - NP_001034390
swissprot - Q5ZJL7
Ensembl - ENSGALG00000008218
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddb2ENSDARG00000041140Danio rerio
 DDB2ENSG00000134574Homo sapiens
 Ddb2ENSMUSG00000002109Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR033312  DNA damage-binding protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006290 pyrimidine dimer repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035518 histone H2A monoubiquitination IEA
 biological_processGO:0051865 protein autoubiquitination IEA
 biological_processGO:0070914 UV-damage excision repair IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031465 Cul4B-RING E3 ubiquitin ligase complex IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0080008 Cul4-RING E3 ubiquitin ligase complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003684 damaged DNA binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases
DNA Damage Recognition in GG-NER
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008559 CUL4B / cullin 4B / A2A432* / Q13620*  / complex
 ENSGALG00000006357 XPC / XPC complex subunit, DNA damage recognition and repair factor / P51612* / Q01831* / xeroderma pigmentosum, complementation group C*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction / complex
 ENSGALG00000010805 USP24 / ubiquitin specific peptidase 24 / B1AY13* / Q9UPU5*  / complex
 ENSGALG00000007510 CETN2 / CETN1* / Q9R1K9* / P41209* / Q12798* / P41208* / centrin 2* / centrin 1*  / complex / reaction
 ENSGALG00000009228 PARP1 / poly / P09874* / poly(ADP-ribose) polymerase 1* / poly (ADP-ribose) polymerase family, member 1*  / reaction / complex
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction / complex
 ENSGALG00000042333 DDB1 / Q805F9 / DNA damage-binding protein 1 / Q16531* / Q3U1J4* / damage specific DNA binding protein 1*  / complex
 ENSGALG00000011993 RBX1 / ring-box 1 / P62877* / P62878* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex






 

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