ENSDARG00000041140


Danio rerio

Features
Gene ID: ENSDARG00000041140
  
Biological name :ddb2
  
Synonyms : damage-specific DNA binding protein 2 / ddb2 / Q2YDS1
  
Possible biological names infered from orthology : DNA damage-binding protein 2 / Q92466 / Q99J79
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 20468157
Gene end: 20482855
  
Corresponding Affymetrix probe sets: Dr.25576.1.A1_at (Zebrafish Array)   NM_001083061_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000119193
Ensembl peptide - ENSDARP00000060301
Ensembl peptide - ENSDARP00000091438
Ensembl peptide - ENSDARP00000145040
NCBI entrez gene - 100004133     See in Manteia.
RefSeq - NM_001083061
RefSeq - XM_005159034
RefSeq Peptide - NP_001076530
swissprot - Q2YDS1
swissprot - Z4YI04
swissprot - Z4YIW2
ZFIN ID - ZDB-GENE-050419-169
Ensembl - ENSDARG00000041140
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DDB2ENSGALG00000008218Gallus gallus
 DDB2ENSG00000134574Homo sapiens
 Ddb2ENSMUSG00000002109Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR033312  DNA damage-binding protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0080008 Cul4-RING E3 ubiquitin ligase complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003684 damaged DNA binding IEA


Pathways (from Reactome)
Pathway description
DNA Damage Recognition in GG-NER
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000019529 parp1 / poly (ADP-ribose) polymerase 1 / P09874* / poly (ADP-ribose) polymerase family, member 1*  / complex / reaction
 ENSDARG00000060510 cul4b / cullin 4B / A2A432* / Q13620*  / complex
 ENSDARG00000038030 rbx1 / ring-box 1, E3 ubiquitin protein ligase / P62878* / P62877* / ring-box 1* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex
 ENSDARG00000039754 xpc / xeroderma pigmentosum, complementation group C / P51612* / Q01831* / XPC complex subunit, DNA damage recognition and repair factor*  / complex / reaction
 ENSDARG00000101510 cetn2 / centrin, EF-hand protein, 2 / CETN1* / Q9R1K9* / P41209* / Q12798* / P41208* / centrin 2* / centrin 1*  / reaction / complex
 ENSDARG00000096578 cul4a / cullin 4A / Q13619* / Q3TCH7*  / complex
 ENSDARG00000021550 rad23b / RAD23 homolog B, nucleotide excision repair protein / P54727*  / complex / reaction






 

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