ENSDARG00000021550


Danio rerio

Features
Gene ID: ENSDARG00000021550
  
Biological name :rad23b
  
Synonyms : rad23b / RAD23 homolog B, nucleotide excision repair protein
  
Possible biological names infered from orthology : P54727 / P54728 / UV excision repair B
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 382400
Gene end: 410449
  
Corresponding Affymetrix probe sets: Dr.15153.1.A1_at (Zebrafish Array)   Dr.15153.2.S1_at (Zebrafish Array)   NM_200564_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000107646
Ensembl peptide - ENSDARP00000145115
NCBI entrez gene - 393536     See in Manteia.
RefSeq - NM_200564
RefSeq Peptide - NP_956858
swissprot - F1R6E5
ZFIN ID - ZDB-GENE-040426-1487
Ensembl - ENSDARG00000021550
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAD23BENSGALG00000015540Gallus gallus
 P54727ENSG00000119318Homo sapiens
 P54728ENSMUSG00000028426Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rad23ab / RAD23 homolog A, nucleotide excision repair protein bENSDARG0000005898460
rad23aa / RAD23 homolog A, nucleotide excision repair protein a / RAD23A* / P54725* / P54726* / RAD23 homolog A, nucleotide excision repair protein*ENSDARG0000002000157


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR004806  UV excision repair protein Rad23
 IPR006636  Heat shock chaperonin-binding
 IPR009060  UBA-like superfamily
 IPR015360  XPC-binding domain
 IPR015940  Ubiquitin-associated domain
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003684 damaged DNA binding IEA


Pathways (from Reactome)
Pathway description
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Josephin domain DUBs
DNA Damage Recognition in GG-NER
Formation of Incision Complex in GG-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000019529 parp1 / poly (ADP-ribose) polymerase 1 / P09874* / poly (ADP-ribose) polymerase family, member 1*  / complex / reaction
 ENSDARG00000028119 Q6NV25 / sumo3a / small ubiquitin-like modifier 3a / SUMO3* / Q9Z172* / P55854* / small ubiquitin-like modifier 3*  / complex
 ENSDARG00000035993 sumo3b / small ubiquitin-like modifier 3b / SUMO3* / P55854* / small ubiquitin-like modifier 3*  / complex
 ENSDARG00000044267 sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *  / complex
 ENSDARG00000060510 cul4b / cullin 4B / A2A432* / Q13620*  / reaction / complex
 ENSDARG00000039754 xpc / xeroderma pigmentosum, complementation group C / P51612* / Q01831* / XPC complex subunit, DNA damage recognition and repair factor*  / reaction / complex
 ENSDARG00000038030 rbx1 / ring-box 1, E3 ubiquitin protein ligase / P62878* / P62877* / ring-box 1* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / reaction / complex
 ENSDARG00000041140 ddb2 / Q2YDS1 / damage-specific DNA binding protein 2 / Q92466* / Q99J79* / DNA damage-binding protein 2 *  / reaction / complex
 ENSDARG00000099274 atxn3 / ataxin 3 / ATXN3L* / Q9H3M9* / P54252* / ataxin 3 like*  / reaction / complex
 ENSDARG00000101510 cetn2 / centrin, EF-hand protein, 2 / CETN1* / Q9R1K9* / P41209* / Q12798* / P41208* / centrin 2* / centrin 1*  / complex / reaction
 ENSDARG00000096578 cul4a / cullin 4A / Q13619* / Q3TCH7*  / reaction / complex
 ENSDARG00000102741 sumo2b / Q6DHL4 / small ubiquitin-like modifier 2b / SUMO4* / SUMO2* / Q6EEV6* / P61956* / P61957* / small ubiquitin-like modifier 4* / small ubiquitin-like modifier 2*  / complex






 

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