ENSGALG00000008931


Gallus gallus

Features
Gene ID: ENSGALG00000008931
  
Biological name :COMMD1
  
Synonyms : COMMD1 / copper metabolism domain containing 1
  
Possible biological names infered from orthology : COMM domain-containing protein 1 / Gm28048 / Q8K4M5 / Q8N668
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 8983259
Gene end: 9052594
  
Corresponding Affymetrix probe sets: Gga.4534.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014499
Ensembl peptide - ENSGALP00000061760
Ensembl peptide - ENSGALP00000052410
Ensembl peptide - ENSGALP00000044594
NCBI entrez gene - 769006     See in Manteia.
RefSeq - XM_015278116
RefSeq - XM_001231775
RefSeq - XM_004940200
RefSeq - XM_015278114
swissprot - A0A1L1RSH7
swissprot - A0A1D5PHX9
swissprot - A0A1D5NW58
swissprot - F1NKT9
Ensembl - ENSGALG00000008931
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 commd1ENSDARG00000031203Danio rerio
 COMMD1ENSG00000173163Homo sapiens
 Commd1ENSMUSG00000051355Mus musculus
 Gm28048ENSMUSG00000098650Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR017920  COMM domain
 IPR033776  COMMD1 N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006893 Golgi to plasma membrane transport IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination IBA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0048227 plasma membrane to endosome transport IEA
 biological_processGO:0055070 copper ion homeostasis IEA
 biological_processGO:1902306 negative regulation of sodium ion transmembrane transport IBA
 biological_processGO:2000009 negative regulation of protein localization to cell surface IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IBA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0031462 Cul2-RING ubiquitin ligase complex IEA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IEA
 molecular_functionGO:0070300 phosphatidic acid binding IEA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008559 CUL4B / cullin 4B / A2A432* / Q13620*  / complex
 ENSGALG00000002267 DCUN1D3 / defective in cullin neddylation 1 domain containing 3 / Q8IWE4* / Q8K0V2* / DCN1-like protein 3 *  / complex / reaction
 ENSGALG00000006474 SKP1 / Q5ZKF5 / S-phase kinase-associated protein 1 / Skp1a* / Q9WTX5* / P63208* / AC104109.3* / S-phase kinase-associated protein 1A*  / complex
 ENSGALG00000036941 CUL1 / cullin 1 / Q13616* / Q9WTX6* / Mus musculus cullin 1 (Cul1), transcript variant 3, mRNA.*  / complex
 ENSGALG00000042333 DDB1 / Q805F9 / DNA damage-binding protein 1 / Q16531* / Q3U1J4* / damage specific DNA binding protein 1*  / complex
 ENSGALG00000011993 RBX1 / ring-box 1 / P62877* / P62878* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex






 

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