ENSGALG00000009837


Gallus gallus

Features
Gene ID: ENSGALG00000009837
  
Biological name :DTL
  
Synonyms : Denticleless protein homolog / DTL / Q5ZJW8
  
Possible biological names infered from orthology : denticleless E3 ubiquitin protein ligase homolog / Q3TLR7 / Q9NZJ0
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 22052274
Gene end: 22074536
  
Corresponding Affymetrix probe sets: Gga.15801.1.S1_s_at (Chicken Array)   GgaAffx.12419.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000057985
Ensembl peptide - ENSGALP00000015973
NCBI entrez gene - 421373     See in Manteia.
RefSeq - NM_001031048
RefSeq Peptide - NP_001026219
swissprot - Q5ZJW8
swissprot - A0A1D5PYD4
Ensembl - ENSGALG00000009837
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dtlENSDARG00000023002Danio rerio
 DTLENSG00000143476Homo sapiens
 DtlENSMUSG00000037474Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006513 protein monoubiquitination IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus ISS
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0010971 positive regulation of G2/M transition of mitotic cell cycle IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0019985 translesion synthesis IEA
 biological_processGO:0045732 positive regulation of protein catabolic process IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0072425 signal transduction involved in G2 DNA damage checkpoint IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031464 Cul4A-RING E3 ubiquitin ligase complex IEA
 cellular_componentGO:0031465 Cul4B-RING E3 ubiquitin ligase complex IEA
 cellular_componentGO:0080008 Cul4-RING E3 ubiquitin ligase complex IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA


Pathways (from Reactome)
Pathway description
Recognition of DNA damage by PCNA-containing replication complex
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008559 CUL4B / cullin 4B / A2A432* / Q13620*  / complex
 ENSGALG00000003072 RPA1 / Q5ZJJ2 / Replication protein A 70 kDa DNA-binding subunit / Q8VEE4* / P27694* / replication protein A1*  / complex / reaction
 ENSGALG00000011993 RBX1 / ring-box 1 / P62877* / P62878* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction
 ENSGALG00000000734 RPA2 / RPA4* / Q13156* / P15927* / replication protein A2* / replication protein A4*  / complex / reaction
 ENSGALG00000029292 PCNA / Q9DEA3 / Proliferating cell nuclear antigen / P17918* / P12004* / Pcna-ps2*  / reaction / complex
 ENSGALG00000042333 DDB1 / Q805F9 / DNA damage-binding protein 1 / Q16531* / Q3U1J4* / damage specific DNA binding protein 1*  / complex
 ENSGALG00000010700 RPA3 / replication protein A3 / P35244* / Q9CQ71* / Replication protein A 14 kDa subunit *  / reaction / complex
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction






 

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