ENSGALG00000010103


Gallus gallus

Features
Gene ID: ENSGALG00000010103
  
Biological name :FBXW7
  
Synonyms : F-box and WD repeat domain containing 7 / FBXW7
  
Possible biological names infered from orthology : F-box/WD repeat-containing protein 7 / Q8VBV4 / Q969H0
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 33933954
Gene end: 34029163
  
Corresponding Affymetrix probe sets: GgaAffx.6345.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000016409
Ensembl peptide - ENSGALP00000050497
swissprot - A0A1D5PCK8
swissprot - F1N9W1
Ensembl - ENSGALG00000010103
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxw7ENSDARG00000060994Danio rerio
 FBXW7ENSG00000109670Homo sapiens
 Fbxw7ENSMUSG00000028086Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000001733668
ZNF106 / zinc finger protein 106 / Q9H2Y7* / Zfp106*ENSGALG0000000908121
BTRC / beta-transducin repeat containing E3 ubiquitin protein ligase / Q3ULA2* / Q9Y297* / F-box/WD repeat-containing protein 1A *ENSGALG0000000782021
FBXW11 / F-box and WD repeat domain containing 11 / Q5SRY7* / Q9UKB1* / F-box/WD repeat-containing protein 11 *ENSGALG0000000222920
TRAF7 / TNF receptor associated factor 7 / Q6Q0C0*ENSGALG0000000576717
CDRT1* / Q5XX13* / FBXW10* / O95170* / Q5SUS0* / CMT1A duplicated region transcript 1* / F-box/WD repeat-containing protein 10 * / F-box and WD repeat domain containing 10*ENSGALG0000004456715
FBXW2 / F-box and WD repeat domain containing 2 / Q9UKT8*ENSGALG0000000086414
WDR86 / WD repeat domain 86 / Q86TI4*ENSGALG0000001969014


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR001810  F-box domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007062 sister chromatid cohesion IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination IEA
 biological_processGO:0032876 negative regulation of DNA endoreduplication IEA
 biological_processGO:0045741 positive regulation of epidermal growth factor-activated receptor activity IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0051443 positive regulation of ubiquitin-protein transferase activity IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:1901800 positive regulation of proteasomal protein catabolic process IEA
 biological_processGO:1903146 regulation of autophagy of mitochondrion IEA
 biological_processGO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IEA
 biological_processGO:2000060 positive regulation of ubiquitin-dependent protein catabolic process IEA
 biological_processGO:2001205 negative regulation of osteoclast development IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IEA
 cellular_componentGO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex IEA
 molecular_functionGO:0030332 cyclin binding IEA
 molecular_functionGO:0030674 protein binding, bridging IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0050816 phosphothreonine residue binding IEA
 molecular_functionGO:0097027 ubiquitin-protein transferase activator activity IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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