ENSGALG00000011020


Gallus gallus

Features
Gene ID: ENSGALG00000011020
  
Biological name :CYCS
  
Synonyms : CYCS / Cytochrome c / P67881
  
Possible biological names infered from orthology : cytochrome c, somatic / Gm10053 / P62897 / P99999 / predicted gene 10053
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 31819123
Gene end: 31821634
  
Corresponding Affymetrix probe sets: Gga.5919.1.S1_at (Chicken Array)   Gga.5919.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017934
Ensembl peptide - ENSGALP00000063797
NCBI entrez gene - 420624     See in Manteia.
RefSeq - XM_015281453
RefSeq - NM_001079478
RefSeq - XM_015281451
RefSeq - XM_015281452
RefSeq Peptide - NP_001072946
swissprot - P67881
Ensembl - ENSGALG00000011020
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cycsaENSDARG00000095636Danio rerio
 CYCSENSG00000172115Homo sapiens
 CycsENSMUSG00000063694Mus musculus
 P62897ENSMUSG00000058927Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cyct* / P00015* / Cytochrome c, testis-specific *ENSGALG0000004071880


Protein motifs (from Interpro)
Interpro ID Name
 IPR002327  Cytochrome c, class IA/ IB
 IPR009056  Cytochrome c-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c IBA
 biological_processGO:0006123 mitochondrial electron transport, cytochrome c to oxygen IBA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005758 mitochondrial intermembrane space IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0043293 apoptosome IDA
 cellular_componentGO:0070469 respiratory chain IEA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Release of apoptotic factors from the mitochondria
Formation of apoptosome
Activation of caspases through apoptosome-mediated cleavage
Transcriptional activation of mitochondrial biogenesis
Detoxification of Reactive Oxygen Species
Respiratory electron transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000012692 SIRT5 / E1BRE2 / NAD-dependent protein deacylase sirtuin-5, mitochondrial / Q8K2C6* / Q9NXA8* / sirtuin 5*  / reaction
 ENSGALG00000011020 CYCS / P67881 / Cytochrome c / P99999* / P62897* / Gm10053* / predicted gene 10053* / cytochrome c, somatic*  / reaction
 ENSGALG00000001366 CASP9 / caspase 9 / P55211* / Q8C3Q9* / Mus musculus caspase 9 (Casp9), transcript variant 3, mRNA.*  / reaction / complex
 ENSGALG00000011531 APAF1 / apoptotic peptidase activating factor 1 / O14727* / O88879* / Apoptotic protease-activating factor 1 *  / reaction / complex






 

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