ENSGALG00000011248


Gallus gallus

Features
Gene ID: ENSGALG00000011248
  
Biological name :PLCL2
  
Synonyms : phospholipase C like 2 / PLCL2
  
Possible biological names infered from orthology : Inactive phospholipase C-like protein 2 / Q8K394 / Q9UPR0
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 34592366
Gene end: 34683688
  
Corresponding Affymetrix probe sets: GgaAffx.7149.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018326
Ensembl peptide - ENSGALP00000046374
NCBI entrez gene - 420645     See in Manteia.
RefSeq - XM_015281813
swissprot - A0A1D5P143
swissprot - F1P354
Ensembl - ENSGALG00000011248
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plcl2ENSDARG00000098826Danio rerio
 PLCL2ENSG00000154822Homo sapiens
 Plcl2ENSMUSG00000038910Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLCL1 / phospholipase C like 1 (inactive) / Q15111* / Q3USB7* / Inactive phospholipase C-like protein 1 *ENSGALG0000000811361
ENSGALG0000000334559
PLCH1 / phospholipase C eta 1 / Q4KWH5* / Q4KWH8* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 *ENSGALG0000001031230
PLCH2 / phospholipase C eta 2 / A2AP18* / O75038* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 *ENSGALG0000000120729
PLCD4 / phospholipase C delta 4 / Q8K3R3* / Q9BRC7*ENSGALG0000002668727
PLCD1 / phospholipase C delta 1 / P51178* / Q8R3B1* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 *ENSGALG0000000580526
PLCB2 / phospholipase C beta 2 / A3KGF7* / Q00722* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 *ENSGALG0000004210524
PLCB1 / phospholipase C beta 1 / Q9NQ66* / Q9Z1B3* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 *ENSGALG0000000887524
PLCD3 / phospholipase C delta 3 / Q8K2J0* / Q8N3E9* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 *ENSGALG0000004521224
PLCB4 / phospholipase C beta 4 / Q15147*ENSGALG0000000890723
PLCZ1 / Q2VRL0 / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 / Q86YW0* / Q8K4D7* / phospholipase C zeta 1*ENSGALG0000001312322


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000909  Phosphatidylinositol-specific phospholipase C, X domain
 IPR001192  Phosphoinositide phospholipase C family
 IPR001711  Phospholipase C, phosphatidylinositol-specific, Y domain
 IPR001849  Pleckstrin homology domain
 IPR011992  EF-hand domain pair
 IPR011993  PH-like domain superfamily
 IPR015359  Phosphoinositide-specific phospholipase C, EF-hand-like domain
 IPR017946  PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002322 B cell proliferation involved in immune response IEA
 biological_processGO:0002337 B-1a B cell differentiation IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007214 gamma-aminobutyric acid signaling pathway IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0032228 regulation of synaptic transmission, GABAergic IEA
 biological_processGO:0033135 regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0050859 negative regulation of B cell receptor signaling pathway IEA
 biological_processGO:1900122 positive regulation of receptor binding IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0004435 phosphatidylinositol phospholipase C activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0050811 GABA receptor binding IEA
 molecular_functionGO:0070679 inositol 1,4,5 trisphosphate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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