ENSGALG00000026687


Gallus gallus

Features
Gene ID: ENSGALG00000026687
  
Biological name :PLCD4
  
Synonyms : phospholipase C delta 4 / PLCD4
  
Possible biological names infered from orthology : Q8K3R3 / Q9BRC7
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 22607784
Gene end: 22613295
  
Corresponding Affymetrix probe sets: GgaAffx.7240.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046163
Ensembl peptide - ENSGALP00000043203
NCBI entrez gene - 424214     See in Manteia.
RefSeq - XM_015290075
RefSeq - XM_015290073
RefSeq - XM_015290074
RefSeq - XM_004942870
RefSeq - XM_004942871
RefSeq - XM_004942874
RefSeq - XM_004942875
RefSeq - XM_015290068
RefSeq - XM_015290069
RefSeq - XM_015290071
RefSeq - XM_015290072
swissprot - R4GLW0
swissprot - A0A1D5P0I5
Ensembl - ENSGALG00000026687
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plcd4aENSDARG00000057975Danio rerio
 plcd4bENSDARG00000040684Danio rerio
 PLCD4ENSG00000115556Homo sapiens
 Plcd4ENSMUSG00000026173Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLCD1 / phospholipase C delta 1 / P51178* / Q8R3B1* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 *ENSGALG0000000580547
PLCD3 / phospholipase C delta 3 / Q8K2J0* / Q8N3E9* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 *ENSGALG0000004521244
PLCH1 / phospholipase C eta 1 / Q4KWH5* / Q4KWH8* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 *ENSGALG0000001031239
PLCH2 / phospholipase C eta 2 / A2AP18* / O75038* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 *ENSGALG0000000120739
ENSGALG0000000334538
PLCL2 / phospholipase C like 2 / Q8K394* / Q9UPR0* / Inactive phospholipase C-like protein 2 *ENSGALG0000001124838
PLCZ1 / Q2VRL0 / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 / Q86YW0* / Q8K4D7* / phospholipase C zeta 1*ENSGALG0000001312335
PLCL1 / phospholipase C like 1 (inactive) / Q15111* / Q3USB7* / Inactive phospholipase C-like protein 1 *ENSGALG0000000811335
PLCB1 / phospholipase C beta 1 / Q9NQ66* / Q9Z1B3* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 *ENSGALG0000000887530
PLCB4 / phospholipase C beta 4 / Q15147*ENSGALG0000000890729
PLCB2 / phospholipase C beta 2 / A3KGF7* / Q00722* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 *ENSGALG0000004210527


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000909  Phosphatidylinositol-specific phospholipase C, X domain
 IPR001192  Phosphoinositide phospholipase C family
 IPR001711  Phospholipase C, phosphatidylinositol-specific, Y domain
 IPR001849  Pleckstrin homology domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR011993  PH-like domain superfamily
 IPR015359  Phosphoinositide-specific phospholipase C, EF-hand-like domain
 IPR017946  PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
 IPR018247  EF-Hand 1, calcium-binding site
 IPR028387  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007340 acrosome reaction IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0046488 phosphatidylinositol metabolic process IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0004435 phosphatidylinositol phospholipase C activity IEA
 molecular_functionGO:0004629 phospholipase C activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of IP3 and IP4 in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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