Manteia

ENSGALG00000012273

Gallus gallus

Features

Gene ID:	ENSGALG00000012273

Biological name :	SOS2

Synonyms :	SOS2 / SOS Ras/Rho guanine nucleotide exchange factor 2

Possible biological names infered from orthology :	Q02384 / Q07890 / Son of sevenless homolog 2

Species:	Gallus gallus

Chr. number:	5
Strand:	-1
Band:
Gene start:	57854053
Gene end:	57900599

Corresponding Affymetrix probe sets:	Gga.10089.1.S1_at (Chicken Array) Gga.10089.1.S1_s_at (Chicken Array) Gga.7084.1.S1_at (Chicken Array) GgaAffx.23855.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000020023 NCBI entrez gene - 423572 See in Manteia. RefSeq - XM_015276737 swissprot - F1N8Q9 Ensembl - ENSGALG00000012273

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
SOS1 / SOS Ras/Rac guanine nucleotide exchange factor 1 / Q07889* / Q62245* / Son of sevenless homolog 1 *	ENSGALG00000039450	71
RAPGEF1 / Rap guanine nucleotide exchange factor 1 / Q13905* / Rap guanine nucleotide exchange factor (GEF) 1*	ENSGALG00000003712	16
RASGRF1 / Ras protein specific guanine nucleotide releasing factor 1 / P27671* / Q13972*	ENSGALG00000008262	12
RASGRF2 / Ras protein specific guanine nucleotide releasing factor 2 / O14827* / ras-specific guanine nucleotide-releasing factor 2 *	ENSGALG00000015598	12
RGL4* / RGL2* / Q12967* / Q61193* / RALGDS* / Q8IZJ4* / O15211* / Q03385* / AL162417.1* / ral guanine nucleotide dissociation stimulator* / ral guanine nucleotide dissociation stimulator li...	ENSGALG00000003412	11
RGL1 / ral guanine nucleotide dissociation stimulator like 1 / Q60695* / Q9NZL6* / Mus musculus ral guanine nucleotide dissociation stimulator,-like 1 (Rgl1), transcript variant 2, mRNA.*	ENSGALG00000004728	10
RALGPS1 / Ral GEF with PH domain and SH3 binding motif 1 / A2AR50* / Q5JS13* / Ras-specific guanine nucleotide-releasing factor RalGPS1 *	ENSGALG00000000906	7
Q5ZJK0 / RALGPS2 / Ras-specific guanine nucleotide-releasing factor RalGPS1 / Q9ERD6* / Q86X27* / Ral GEF with PH domain and SH3 binding motif 2*	ENSGALG00000004273	7

Protein motifs (from Interpro)

Interpro ID	Name
IPR000219	Dbl homology (DH) domain
IPR000651	Ras-like guanine nucleotide exchange factor, N-terminal
IPR001849	Pleckstrin homology domain
IPR001895	Ras guanine-nucleotide exchange factors catalytic domain
IPR007125	Histone H2A/H2B/H3
IPR009072	Histone-fold
IPR011993	PH-like domain superfamily
IPR019804	Ras guanine-nucleotide exchange factor, conserved site
IPR023578	Ras guanine nucleotide exchange factor domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007264	small GTPase mediated signal transduction	IEA
biological_process	GO:0035023	regulation of Rho protein signal transduction	IEA
biological_process	GO:0065009	regulation of molecular function	IEA
cellular_component	GO:0005622	intracellular	IEA
molecular_function	GO:0003677	DNA binding	IEA
molecular_function	GO:0005085	guanyl-nucleotide exchange factor activity	IEA
molecular_function	GO:0005089	Rho guanyl-nucleotide exchange factor activity	IEA
molecular_function	GO:0046982	protein heterodimerization activity	IEA

Pathways (from Reactome)

Pathway description

NRAGE signals death through JNK

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr