ENSGALG00000004273


Gallus gallus

Features
Gene ID: ENSGALG00000004273
  
Biological name :RALGPS2
  
Synonyms : Q5ZJK0 / RALGPS2 / Ras-specific guanine nucleotide-releasing factor RalGPS1
  
Possible biological names infered from orthology : Q86X27 / Q9ERD6 / Ral GEF with PH domain and SH3 binding motif 2
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 6315603
Gene end: 6425139
  
Corresponding Affymetrix probe sets: Gga.17662.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050603
Ensembl peptide - ENSGALP00000006783
Ensembl peptide - ENSGALP00000045211
NCBI entrez gene - 424429     See in Manteia.
RefSeq - XM_015290288
RefSeq - NM_001006532
RefSeq - XM_015290285
RefSeq - XM_015290286
RefSeq - XM_015290287
RefSeq - XM_015290282
RefSeq - XM_015290283
RefSeq - XM_015290284
RefSeq Peptide - NP_001006532
swissprot - Q5ZJK0
swissprot - A0A1D5PCW2
Ensembl - ENSGALG00000004273
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ralgps2ENSDARG00000026519Danio rerio
 Q86X27ENSG00000116191Homo sapiens
 Q9ERD6ENSMUSG00000026594Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RALGPS1 / Ral GEF with PH domain and SH3 binding motif 1 / A2AR50* / Q5JS13* / Ras-specific guanine nucleotide-releasing factor RalGPS1 *ENSGALG0000000090663
RGL4* / RGL2* / Q12967* / Q61193* / RALGDS* / Q8IZJ4* / O15211* / Q03385* / AL162417.1* / ral guanine nucleotide dissociation stimulator* / ral guanine nucleotide dissociation stimulator li...ENSGALG0000000341221
RGL1 / ral guanine nucleotide dissociation stimulator like 1 / Q60695* / Q9NZL6* / Mus musculus ral guanine nucleotide dissociation stimulator,-like 1 (Rgl1), transcript variant 2, mRNA.*ENSGALG0000000472821
SOS1 / SOS Ras/Rac guanine nucleotide exchange factor 1 / Q07889* / Q62245* / Son of sevenless homolog 1 *ENSGALG0000003945016
SOS2 / SOS Ras/Rho guanine nucleotide exchange factor 2 / Q02384* / Q07890* / Son of sevenless homolog 2 *ENSGALG0000001227315
RASGRF1 / Ras protein specific guanine nucleotide releasing factor 1 / P27671* / Q13972*ENSGALG0000000826214
RASGRF2 / Ras protein specific guanine nucleotide releasing factor 2 / O14827* / ras-specific guanine nucleotide-releasing factor 2 *ENSGALG0000001559813
RAPGEF1 / Rap guanine nucleotide exchange factor 1 / Q13905* / Rap guanine nucleotide exchange factor (GEF) 1*ENSGALG0000000371213


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR011993  PH-like domain superfamily
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR030708  Ras-specific guanine nucleotide-releasing factor RalGPS1/2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0032485 regulation of Ral protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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