ENSG00000116191


Homo sapiens

Features
Gene ID: ENSG00000116191
  
Biological name :RALGPS2
  
Synonyms : Q86X27 / Ral GEF with PH domain and SH3 binding motif 2 / RALGPS2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q25.2
Gene start: 178725147
Gene end: 178921841
  
Corresponding Affymetrix probe sets: 220338_at (Human Genome U133 Plus 2.0 Array)   227224_at (Human Genome U133 Plus 2.0 Array)   227533_at (Human Genome U133 Plus 2.0 Array)   232112_at (Human Genome U133 Plus 2.0 Array)   242458_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000313613
Ensembl peptide - ENSP00000356606
Ensembl peptide - ENSP00000356607
Ensembl peptide - ENSP00000405903
Ensembl peptide - ENSP00000356604
NCBI entrez gene - 55103     See in Manteia.
OMIM - 617819
RefSeq - XM_017001591
RefSeq - NM_001286247
RefSeq - NM_152663
RefSeq - XM_006711410
RefSeq - XM_006711411
RefSeq - XM_011509688
RefSeq Peptide - NP_689876
RefSeq Peptide - NP_001273176
swissprot - H0Y338
swissprot - H7C2H2
swissprot - Q86X27
swissprot - A0A0A0MR31
Ensembl - ENSG00000116191
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ralgps2ENSDARG00000026519Danio rerio
 Q5ZJK0ENSGALG00000004273Gallus gallus
 Q9ERD6ENSMUSG00000026594Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5JS13 / RALGPS1 / Ral GEF with PH domain and SH3 binding motif 1ENSG0000013682861
Q12967 / RALGDS / ral guanine nucleotide dissociation stimulatorENSG0000016027122
AL162417.1ENSG0000028524522
RGL1 / Q9NZL6 / ral guanine nucleotide dissociation stimulator like 1ENSG0000014334421
RGL3 / Q3MIN7 / ral guanine nucleotide dissociation stimulator like 3ENSG0000020551721
RGL2 / O15211 / ral guanine nucleotide dissociation stimulator like 2ENSG0000023744119
SOS1 / Q07889 / SOS Ras/Rac guanine nucleotide exchange factor 1ENSG0000011590417
SOS2 / Q07890 / SOS Ras/Rho guanine nucleotide exchange factor 2ENSG0000010048516
O14827 / RASGRF2 / Ras protein specific guanine nucleotide releasing factor 2ENSG0000011331913
Q13972 / RASGRF1 / Ras protein specific guanine nucleotide releasing factor 1ENSG0000005833513
RGL4 / Q8IZJ4 / ral guanine nucleotide dissociation stimulator like 4ENSG0000015949613
Q13905 / RAPGEF1 / Rap guanine nucleotide exchange factor 1ENSG0000010726313


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR011993  PH-like domain superfamily
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR030708  Ras-specific guanine nucleotide-releasing factor RalGPS1/2
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0032485 regulation of Ral protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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