ENSDARG00000026519


Danio rerio

Features
Gene ID: ENSDARG00000026519
  
Biological name :ralgps2
  
Synonyms : Ral GEF with PH domain and SH3 binding motif 2 / ralgps2
  
Possible biological names infered from orthology : Q86X27 / Q9ERD6
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 15933028
Gene end: 16156419
  
Corresponding Affymetrix probe sets: Dr.15757.2.A1_at (Zebrafish Array)   Dr.17213.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000004445
Ensembl peptide - ENSDARP00000035914
swissprot - F1REU9
swissprot - Q5RH52
ZFIN ID - ZDB-GENE-040426-1212
Ensembl - ENSDARG00000026519
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5ZJK0ENSGALG00000004273Gallus gallus
 Q86X27ENSG00000116191Homo sapiens
 Q9ERD6ENSMUSG00000026594Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
B0UXH6 / ralgps1 / Ral GEF with PH domain and SH3 binding motif 1 / Q5JS13* / A2AR50* / Ras-specific guanine nucleotide-releasing factor RalGPS1 *ENSDARG0000006837058
rgl1 / ral guanine nucleotide dissociation stimulator-like 1 / Q60695* / Q9NZL6* / Mus musculus ral guanine nucleotide dissociation stimulator,-like 1 (Rgl1), transcript variant 2, mRNA.*ENSDARG0000000598919
si:ch211-251j10.3 / RGL4* / RGL2* / Q61193* / Q8IZJ4* / RALGDS* / O15211* / Q03385* / Q12967* / AL162417.1* / ral guanine nucleotide dissociation stimulator* / ral guanine nucleotide dissoc...ENSDARG0000004240918
rgl3a / ral guanine nucleotide dissociation stimulator-like 3a / RGL3* / Q3MIN7* / Q3UYI5* / ral guanine nucleotide dissociation stimulator like 3*ENSDARG0000007121318
rgl2 / ral guanine nucleotide dissociation stimulator-like 2ENSDARG0000000772717
sos2 / son of sevenless homolog 2 (Drosophila) / Q02384* / Q07890* / Son of sevenless homolog 2 * / SOS Ras/Rho guanine nucleotide exchange factor 2*ENSDARG0000006050616
sos1 / son of sevenless homolog 1 (Drosophila) / Q07889* / Q62245* / Son of sevenless homolog 1 * / SOS Ras/Rac guanine nucleotide exchange factor 1*ENSDARG0000010050315
rasgrf2a / Ras protein-specific guanine nucleotide-releasing factor 2a / O14827* / RASGRF2* / Ras protein specific guanine nucleotide releasing factor 2*ENSDARG0000007505414
rapgef1a / Rap guanine nucleotide exchange factor (GEF) 1a / Q13905* / RAPGEF1* / Rap guanine nucleotide exchange factor 1* / Rap guanine nucleotide exchange factor (GEF) 1*ENSDARG0000004359313
RASGRF1 / si:ch211-234p18.3 / P27671* / Q13972* / Ras protein specific guanine nucleotide releasing factor 1*ENSDARG0000007382413
rapgef1b / Rap guanine nucleotide exchange factor (GEF) 1bENSDARG0000001597113
A2CEA7 / rasgrf2b / Ras protein-specific guanine nucleotide-releasing factor 2b / O14827* / RASGRF2* / ras-specific guanine nucleotide-releasing factor 2 * / Ras protein specific guanine nu...ENSDARG0000000281613


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR011993  PH-like domain superfamily
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR030708  Ras-specific guanine nucleotide-releasing factor RalGPS1/2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0032485 regulation of Ral protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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