ENSMUSG00000026594


Mus musculus

Features
Gene ID: ENSMUSG00000026594
  
Biological name :Ralgps2
  
Synonyms : Q9ERD6 / Ral GEF with PH domain and SH3 binding motif 2 / Ralgps2
  
Possible biological names infered from orthology : Q86X27
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: G3
Gene start: 156804166
Gene end: 156939626
  
Corresponding Affymetrix probe sets: 10359201 (MoGene1.0st)   1417230_at (Mouse Genome 430 2.0 Array)   1428789_at (Mouse Genome 430 2.0 Array)   1431704_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140055
Ensembl peptide - ENSMUSP00000139822
Ensembl peptide - ENSMUSP00000140108
Ensembl peptide - ENSMUSP00000142004
Ensembl peptide - ENSMUSP00000140342
Ensembl peptide - ENSMUSP00000140230
Ensembl peptide - ENSMUSP00000027886
Ensembl peptide - ENSMUSP00000063872
Ensembl peptide - ENSMUSP00000130581
Ensembl peptide - ENSMUSP00000132533
Ensembl peptide - ENSMUSP00000139618
Ensembl peptide - ENSMUSP00000139645
NCBI entrez gene - 78255     See in Manteia.
MGI - MGI:1925505
RefSeq - XM_017312931
RefSeq - NM_001159965
RefSeq - NM_001159966
RefSeq - NM_001159967
RefSeq - NM_001159968
RefSeq - NM_023884
RefSeq - XM_006497028
RefSeq - XM_006497029
RefSeq - XM_006497030
RefSeq - XM_006497031
RefSeq - XM_006497032
RefSeq - XM_006497033
RefSeq Peptide - NP_001153438
RefSeq Peptide - NP_001153440
RefSeq Peptide - NP_076373
RefSeq Peptide - NP_001153437
RefSeq Peptide - NP_001153439
swissprot - Q9ERD6
swissprot - A0A087WPL3
swissprot - Q8C134
swissprot - A0A0A6YXI6
swissprot - A0A087WQU0
swissprot - A0A087WQA4
swissprot - A0A087WQ61
Ensembl - ENSMUSG00000026594
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ralgps2ENSDARG00000026519Danio rerio
 Q5ZJK0ENSGALG00000004273Gallus gallus
 Q86X27ENSG00000116191Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A2AR50 / Ralgps1 / Ras-specific guanine nucleotide-releasing factor RalGPS1 / Q5JS13* / Ral GEF with PH domain and SH3 binding motif 1*ENSMUSG0000003883163
Q03385 / Ralgds / ral guanine nucleotide dissociation stimulator / Q12967* / AL162417.1*ENSMUSG0000002682121
Rgl3 / Q3UYI5 / Ral guanine nucleotide dissociation stimulator-like 3 / Q3MIN7*ENSMUSG0000004014620
Rgl1 / Q60695 / Mus musculus ral guanine nucleotide dissociation stimulator,-like 1 (Rgl1), transcript variant 2, mRNA. / Q9NZL6* / ral guanine nucleotide dissociation stimulator like 1*ENSMUSG0000002648220
Rgl2 / Q61193 / Ral guanine nucleotide dissociation stimulator-like 2 / O15211*ENSMUSG0000004135419
Sos1 / Q62245 / Son of sevenless homolog 1 / Q07889* / SOS Ras/Rac guanine nucleotide exchange factor 1*ENSMUSG0000002424117
Sos2 / Q02384 / Son of sevenless homolog 2 / Q07890* / SOS Ras/Rho guanine nucleotide exchange factor 2*ENSMUSG0000003480116
P27671 / Rasgrf1 / RAS protein-specific guanine nucleotide-releasing factor 1 / Q13972*ENSMUSG0000003235614
Rapgef1 / Rap guanine nucleotide exchange factor (GEF) 1 / Q13905* / Rap guanine nucleotide exchange factor 1*ENSMUSG0000003984413
Rasgrf2 / ras-specific guanine nucleotide-releasing factor 2 / O14827* / Ras protein specific guanine nucleotide releasing factor 2*ENSMUSG0000002170813


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR011993  PH-like domain superfamily
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR030708  Ras-specific guanine nucleotide-releasing factor RalGPS1/2
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0032485 regulation of Ral protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000480 increased number of ribs "greater than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Rad21ltm1b(KOMP)Wtsi/Rad21ltm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad21ltm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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