ENSMUSG00000040146


Mus musculus

Features
Gene ID: ENSMUSG00000040146
  
Biological name :Rgl3
  
Synonyms : Q3UYI5 / Ral guanine nucleotide dissociation stimulator-like 3 / Rgl3
  
Possible biological names infered from orthology : Q3MIN7
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A3
Gene start: 21968711
Gene end: 21989446
  
Corresponding Affymetrix probe sets: 10591668 (MoGene1.0st)   1431829_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035726
Ensembl peptide - ENSMUSP00000148965
Ensembl peptide - ENSMUSP00000150195
NCBI entrez gene - 71746     See in Manteia.
MGI - MGI:1918996
RefSeq - XM_011242608
RefSeq - NM_023622
RefSeq - XM_006510613
RefSeq - XM_011242607
RefSeq Peptide - NP_076111
swissprot - A0A1L1ST67
swissprot - Q3UYI5
Ensembl - ENSMUSG00000040146
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rgl3aENSDARG00000071213Danio rerio
 RGL3ENSG00000205517Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q03385 / Ralgds / ral guanine nucleotide dissociation stimulator / Q12967* / AL162417.1*ENSMUSG0000002682139
Rgl1 / Q60695 / Mus musculus ral guanine nucleotide dissociation stimulator,-like 1 (Rgl1), transcript variant 2, mRNA. / Q9NZL6* / ral guanine nucleotide dissociation stimulator like 1*ENSMUSG0000002648237
Rgl2 / Q61193 / Ral guanine nucleotide dissociation stimulator-like 2 / O15211*ENSMUSG0000004135435
Sos2 / Q02384 / Son of sevenless homolog 2 / Q07890* / SOS Ras/Rho guanine nucleotide exchange factor 2*ENSMUSG0000003480118
Rasgrf2 / ras-specific guanine nucleotide-releasing factor 2 / O14827* / Ras protein specific guanine nucleotide releasing factor 2*ENSMUSG0000002170818
Sos1 / Q62245 / Son of sevenless homolog 1 / Q07889* / SOS Ras/Rac guanine nucleotide exchange factor 1*ENSMUSG0000002424118
Q9ERD6 / Ralgps2 / Ral GEF with PH domain and SH3 binding motif 2 / Q86X27*ENSMUSG0000002659417
P27671 / Rasgrf1 / RAS protein-specific guanine nucleotide-releasing factor 1 / Q13972*ENSMUSG0000003235617
A2AR50 / Ralgps1 / Ras-specific guanine nucleotide-releasing factor RalGPS1 / Q5JS13* / Ral GEF with PH domain and SH3 binding motif 1*ENSMUSG0000003883117
Rapgef1 / Rap guanine nucleotide exchange factor (GEF) 1 / Q13905* / Rap guanine nucleotide exchange factor 1*ENSMUSG0000003984415


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR000651  Ras-like guanine nucleotide exchange factor, N-terminal
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR019804  Ras guanine-nucleotide exchange factor, conserved site
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR029071  Ubiquitin-like domain superfamily
 IPR030750  Ral guanine nucleotide dissociation stimulator-like 3
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008321 Ral guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0017016 Ras GTPase binding IDA
 molecular_functionGO:0031267 small GTPase binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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