ENSG00000205517


Homo sapiens

Features
Gene ID: ENSG00000205517
  
Biological name :RGL3
  
Synonyms : Q3MIN7 / ral guanine nucleotide dissociation stimulator like 3 / RGL3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.2
Gene start: 11384341
Gene end: 11419342
  
Corresponding Affymetrix probe sets: 1556354_s_at (Human Genome U133 Plus 2.0 Array)   1556355_x_at (Human Genome U133 Plus 2.0 Array)   228877_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454678
Ensembl peptide - ENSP00000455922
Ensembl peptide - ENSP00000456429
Ensembl peptide - ENSP00000464876
Ensembl peptide - ENSP00000466669
Ensembl peptide - ENSP00000369823
Ensembl peptide - ENSP00000377075
NCBI entrez gene - 57139     See in Manteia.
OMIM - 616743
RefSeq - NM_001035223
RefSeq - NM_001161616
RefSeq Peptide - NP_001030300
RefSeq Peptide - NP_001155088
swissprot - Q3MIN7
swissprot - A0A0A0MRX4
swissprot - H3BN42
swissprot - H3BQS8
swissprot - H3BRW0
swissprot - K7EIS7
swissprot - K7EMV7
Ensembl - ENSG00000205517
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rgl3aENSDARG00000071213Danio rerio
 Rgl3ENSMUSG00000040146Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q12967 / RALGDS / ral guanine nucleotide dissociation stimulatorENSG0000016027141
AL162417.1ENSG0000028524541
RGL1 / Q9NZL6 / ral guanine nucleotide dissociation stimulator like 1ENSG0000014334438
RGL2 / O15211 / ral guanine nucleotide dissociation stimulator like 2ENSG0000023744135
SOS1 / Q07889 / SOS Ras/Rac guanine nucleotide exchange factor 1ENSG0000011590419
SOS2 / Q07890 / SOS Ras/Rho guanine nucleotide exchange factor 2ENSG0000010048519
O14827 / RASGRF2 / Ras protein specific guanine nucleotide releasing factor 2ENSG0000011331918
Q86X27 / RALGPS2 / Ral GEF with PH domain and SH3 binding motif 2ENSG0000011619117
Q13972 / RASGRF1 / Ras protein specific guanine nucleotide releasing factor 1ENSG0000005833517
RGL4 / Q8IZJ4 / ral guanine nucleotide dissociation stimulator like 4ENSG0000015949617
Q5JS13 / RALGPS1 / Ral GEF with PH domain and SH3 binding motif 1ENSG0000013682817
Q13905 / RAPGEF1 / Rap guanine nucleotide exchange factor 1ENSG0000010726316


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR000651  Ras-like guanine nucleotide exchange factor, N-terminal
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR019804  Ras guanine-nucleotide exchange factor, conserved site
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR029071  Ubiquitin-like domain superfamily
 IPR030750  Ral guanine nucleotide dissociation stimulator-like 3
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0008321 Ral guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0017016 Ras GTPase binding IEA
 molecular_functionGO:0031267 small GTPase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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