ENSG00000159496


Homo sapiens

Features
Gene ID: ENSG00000159496
  
Biological name :RGL4
  
Synonyms : Q8IZJ4 / ral guanine nucleotide dissociation stimulator like 4 / RGL4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q11.23
Gene start: 23688136
Gene end: 23699176
  
Corresponding Affymetrix probe sets: 235816_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000290691
Ensembl peptide - ENSP00000484573
Ensembl peptide - ENSP00000480308
Ensembl peptide - ENSP00000402142
Ensembl peptide - ENSP00000396252
Ensembl peptide - ENSP00000393115
Ensembl peptide - ENSP00000383951
NCBI entrez gene - 266747     See in Manteia.
OMIM - 612214
RefSeq - XM_017028767
RefSeq - NM_153615
RefSeq Peptide - NP_705843
swissprot - A0A087WWL2
swissprot - E7EPT8
swissprot - H7C063
swissprot - E9PH21
swissprot - Q8IZJ4
swissprot - A0A087X1Z6
swissprot - B5MCW5
Ensembl - ENSG00000159496
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-251j10.3ENSDARG00000042409Danio rerio
 ENSGALG00000003412Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AL162417.1ENSG0000028524541
Q12967 / RALGDS / ral guanine nucleotide dissociation stimulatorENSG0000016027141
RGL1 / Q9NZL6 / ral guanine nucleotide dissociation stimulator like 1ENSG0000014334430
RGL3 / Q3MIN7 / ral guanine nucleotide dissociation stimulator like 3ENSG0000020551726
RGL2 / O15211 / ral guanine nucleotide dissociation stimulator like 2ENSG0000023744126
O14827 / RASGRF2 / Ras protein specific guanine nucleotide releasing factor 2ENSG0000011331923
Q13972 / RASGRF1 / Ras protein specific guanine nucleotide releasing factor 1ENSG0000005833522
Q13905 / RAPGEF1 / Rap guanine nucleotide exchange factor 1ENSG0000010726321
SOS1 / Q07889 / SOS Ras/Rac guanine nucleotide exchange factor 1ENSG0000011590420
SOS2 / Q07890 / SOS Ras/Rho guanine nucleotide exchange factor 2ENSG0000010048519
Q5JS13 / RALGPS1 / Ral GEF with PH domain and SH3 binding motif 1ENSG0000013682817
Q86X27 / RALGPS2 / Ral GEF with PH domain and SH3 binding motif 2ENSG0000011619116


Protein motifs (from Interpro)
Interpro ID Name
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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