ENSGALG00000016830


Gallus gallus

Features
Gene ID: ENSGALG00000016830
  
Biological name :CUL4A
  
Synonyms : CUL4A / cullin 4A
  
Possible biological names infered from orthology : Q13619 / Q3TCH7
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 137511432
Gene end: 137545754
  
Corresponding Affymetrix probe sets: Gga.2453.1.S1_at (Chicken Array)   GgaAffx.10772.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027120
NCBI entrez gene - 418744     See in Manteia.
RefSeq - XM_003640529
RefSeq - XM_004938534
swissprot - F1P2U1
Ensembl - ENSGALG00000016830
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cul4aENSDARG00000096578Danio rerio
 CUL4AENSG00000139842Homo sapiens
 Cul4aENSMUSG00000031446Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CUL4B / cullin 4B / A2A432* / Q13620*ENSGALG0000000855982
CUL3 / cullin 3 / Q13618* / Q9JLV5*ENSGALG0000000510837
CUL1 / cullin 1 / Q13616* / Q9WTX6* / Mus musculus cullin 1 (Cul1), transcript variant 3, mRNA.*ENSGALG0000003694130
CUL2 / cullin-2 / Q13617* / Q9D4H8*ENSGALG0000000709526
CUL5 / cullin 5 / Q93034*ENSGALG0000001716525


Protein motifs (from Interpro)
Interpro ID Name
 IPR001373  Cullin, N-terminal
 IPR011991  ArsR-like helix-turn-helix domain
 IPR016157  Cullin, conserved site
 IPR016158  Cullin homology domain
 IPR016159  Cullin repeat-like-containing domain superfamily
 IPR019559  Cullin protein, neddylation domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IBA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0030853 negative regulation of granulocyte differentiation IEA
 biological_processGO:0035019 somatic stem cell population maintenance IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0051246 regulation of protein metabolic process IEA
 biological_processGO:1900087 positive regulation of G1/S transition of mitotic cell cycle IEA
 biological_processGO:2000001 regulation of DNA damage checkpoint IEA
 biological_processGO:2000819 regulation of nucleotide-excision repair IEA
 cellular_componentGO:0031461 cullin-RING ubiquitin ligase complex IEA
 cellular_componentGO:0031464 Cul4A-RING E3 ubiquitin ligase complex IEA
 cellular_componentGO:0080008 Cul4-RING E3 ubiquitin ligase complex IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Recognition of DNA damage by PCNA-containing replication complex
DNA Damage Recognition in GG-NER
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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