ENSGALG00000007095


Gallus gallus

Features
Gene ID: ENSGALG00000007095
  
Biological name :CUL2
  
Synonyms : CUL2 / cullin-2
  
Possible biological names infered from orthology : Q13617 / Q9D4H8
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 13043021
Gene end: 13088931
  
Corresponding Affymetrix probe sets: Gga.7042.1.S1_a_at (Chicken Array)   Gga.7042.2.S1_at (Chicken Array)   Gga.7042.3.A1_a_at (Chicken Array)   GgaAffx.4436.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046143
Ensembl peptide - ENSGALP00000050746
Ensembl peptide - ENSGALP00000011473
Ensembl peptide - ENSGALP00000037750
NCBI entrez gene - 420467     See in Manteia.
RefSeq - XM_015281339
RefSeq - NM_001030970
RefSeq - XM_015281336
RefSeq - XM_015281337
RefSeq - XM_015281338
RefSeq Peptide - NP_001026141
swissprot - A0A1D5PDA2
swissprot - F1N829
swissprot - F1P2W9
swissprot - A0A1D5P0G5
Ensembl - ENSGALG00000007095
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cul2ENSDARG00000013965Danio rerio
 CUL2ENSG00000108094Homo sapiens
 Cul2ENSMUSG00000024231Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CUL1 / cullin 1 / Q13616* / Q9WTX6* / Mus musculus cullin 1 (Cul1), transcript variant 3, mRNA.*ENSGALG0000003694137
CUL4A / cullin 4A / Q13619* / Q3TCH7*ENSGALG0000001683027
CUL4B / cullin 4B / A2A432* / Q13620*ENSGALG0000000855927
CUL3 / cullin 3 / Q13618* / Q9JLV5*ENSGALG0000000510826
CUL5 / cullin 5 / Q93034*ENSGALG0000001716526


Protein motifs (from Interpro)
Interpro ID Name
 IPR001373  Cullin, N-terminal
 IPR011991  ArsR-like helix-turn-helix domain
 IPR016157  Cullin, conserved site
 IPR016158  Cullin homology domain
 IPR016159  Cullin repeat-like-containing domain superfamily
 IPR019559  Cullin protein, neddylation domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030163 protein catabolic process IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0031461 cullin-RING ubiquitin ligase complex IEA
 cellular_componentGO:0031462 Cul2-RING ubiquitin ligase complex IBA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction
 ENSGALG00000010001 EGLN3 / egl-9 family hypoxia inducible factor 3 / Q9H6Z9*  / complex
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000011993 RBX1 / ring-box 1 / P62877* / P62878* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex
 ENSGALG00000028009 VHL* / VHLL* / P40338* / Q6RSH7* / P40337* / VHL like* / von Hippel-Lindau tumor suppressor*  / complex
 ENSGALG00000010005 EPAS1 / endothelial PAS domain protein 1 / P97481* / Q99814* / Endothelial PAS domain-containing protein 1 *  / complex
 ENSGALG00000021213 UBE2D1 / ubiquitin conjugating enzyme E2 D1 / P51668* / P61080*  / reaction
 ENSGALG00000038128 UBE2D2 / ubiquitin conjugating enzyme E2 D2 / P62838* / P62837* / Ube2d2a* / ubiquitin-conjugating enzyme E2D 2A*  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr