ENSGALG00000031776


Gallus gallus

Features
Gene ID: ENSGALG00000031776
  
Biological name :NFASC
  
Synonyms : Neurofascin / NFASC / O42414
  
Possible biological names infered from orthology : O94856 / Q810U3
  
Species: Gallus gallus
  
Chr. number: 26
Strand: 1
Band:
Gene start: 1889290
Gene end: 1965785
  
Corresponding Affymetrix probe sets: Gga.15999.1.S1_at (Chicken Array)   Gga.4889.1.S1_at (Chicken Array)   Gga.4889.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044802
Ensembl peptide - ENSGALP00000054338
Ensembl peptide - ENSGALP00000048125
Ensembl peptide - ENSGALP00000045559
Ensembl peptide - ENSGALP00000045345
NCBI entrez gene - 419824     See in Manteia.
RefSeq - XM_015298920
RefSeq - XM_015298907
RefSeq - XM_015298908
RefSeq - XM_015298909
RefSeq - XM_015298910
RefSeq - XM_015298911
RefSeq - XM_015298912
RefSeq - XM_015298913
RefSeq - XM_015298914
RefSeq - XM_015298915
RefSeq - XM_015298916
RefSeq - XM_015298917
RefSeq - XM_015298918
RefSeq - XM_015298919
RefSeq - NM_001004493
RefSeq - NM_001004709
RefSeq - NM_001160320
RefSeq - NM_001160321
RefSeq - NM_001160322
RefSeq - NM_001160323
RefSeq - NM_001160324
RefSeq - XM_015298903
RefSeq - XM_015298904
RefSeq - XM_015298905
RefSeq - XM_015298906
RefSeq Peptide - NP_001004709
RefSeq Peptide - NP_001153792
RefSeq Peptide - NP_001153793
RefSeq Peptide - NP_001153794
RefSeq Peptide - NP_001153795
RefSeq Peptide - NP_001153796
RefSeq Peptide - NP_001004493
swissprot - A0A1D5P601
swissprot - A0A1D5NYU8
swissprot - A0A1D5NY88
swissprot - A0A1D5NWR0
swissprot - A0A1D5PN99
swissprot - O42414
Ensembl - ENSGALG00000031776
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU234171.1ENSDARG00000056910Danio rerio
 nfascaENSDARG00000061099Danio rerio
 NFASCENSG00000163531Homo sapiens
 NfascENSMUSG00000026442Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NRCAM / neuronal cell adhesion molecule precursor / Q810U4* / Q92823* / neuronal cell adhesion molecule*ENSGALG0000000951448
CHL1 / cell adhesion molecule L1 like / O00533* / P70232* / Neural cell adhesion molecule L1-like protein Processed neural cell adhesion molecule L1-like protein*ENSGALG0000003785636
CNTN1 / P14781 / Contactin-1 / Q12860* / P12960* / Mus musculus contactin 1 (Cntn1), transcript variant 4, mRNA.*ENSGALG0000000952321
CNTN5 / Q90W79 / Contactin-5 / O94779* / P68500*ENSGALG0000001719721
CNTN4 / contactin 4 / Q69Z26* / Q8IWV2*ENSGALG0000000826321
CNTN6 / contactin 6 / Q9JMB8* / Q9UQ52*ENSGALG0000000792720
CNTN2 / contactin-2 precursor / Q02246* / Q61330* / contactin 2*ENSGALG0000000065320
CNTN3 / contactin 3 / Q07409* / Q9P232*ENSGALG0000000786218


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR026966  Neurofascin/L1/NrCAM, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002175 protein localization to paranode region of axon IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0007422 peripheral nervous system development IEA
 biological_processGO:0019226 transmission of nerve impulse IEA
 biological_processGO:0030913 paranodal junction assembly IEA
 biological_processGO:0042552 myelination IEA
 biological_processGO:0045162 clustering of voltage-gated sodium channels IEA
 biological_processGO:0050808 synapse organization IEA
 biological_processGO:0071205 protein localization to juxtaparanode region of axon IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0033010 paranodal junction IEA
 cellular_componentGO:0033270 paranode region of axon IEA
 cellular_componentGO:0043194 axon initial segment IEA
 cellular_componentGO:0043209 myelin sheath IEA
 molecular_functionGO:0086080 protein binding involved in heterotypic cell-cell adhesion IEA


Pathways (from Reactome)
Pathway description
Neurofascin interactions
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000015436 SDCBP / syndecan binding protein / O00560* / O08992*  / complex / reaction
 ENSGALG00000031776 NFASC / O42414 / Neurofascin / O94856* / Q810U3*  / complex / reaction






 

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